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Merck

L5000

Sigma-Aldrich

N-Lauroylsarcosine, neat

≥95%

Synonym(e):

N-Dodecanoyl-N-methylglycin

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About This Item

Lineare Formel:
CH3(CH2)10CON(CH3)CH2COOH
CAS-Nummer:
Molekulargewicht:
271.40
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12161900
PubChem Substanz-ID:
NACRES:
NA.21

Beschreibung

anionic

Qualitätsniveau

Assay

≥95%

Mol-Gew.

average mol wt 600

Aggregatnummer

2

CMC

14.6

SMILES String

CCCCCCCCCCCC(=O)N(C)CC(O)=O

InChI

1S/C15H29NO3/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19/h3-13H2,1-2H3,(H,18,19)

InChIKey

BACYUWVYYTXETD-UHFFFAOYSA-N

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Allgemeine Beschreibung

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

Physikalische Form

May be liquid at room temperature

Piktogramme

Skull and crossbonesCorrosion

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Manfeng Zhang et al.
PLoS biology, 18(6), e3000748-e3000748 (2020-06-20)
Curli play critical roles in biofilm formation, host cell adhesion, and colonization of inert surfaces in many Enterobacteriaceae. In Escherichia coli, curli biogenesis requires 7 curli-specific gene (csg) products-CsgA through G-working in concert. Of them, CsgG and CsgF are 2
Kunie Ando et al.
The American journal of pathology, 178(2), 803-816 (2011-02-02)
Many models of human tauopathies have been generated in mice by expression of a human mutant tau with maintained expression of mouse endogenous tau. Because murine tau might interfere with the toxic effects of human mutant tau, we generated a
Victoria C de Leeuw et al.
Reproductive toxicology (Elmsford, N.Y.), 98, 107-116 (2020-09-16)
Human embryonic stem cell neuronal differentiation models provide promising in vitro tools for the prediction of developmental neurotoxicity of chemicals. Such models mimic essential elements of human relevant neuronal development, including the differentiation of a variety of brain cell types
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 286(21), 18664-18672 (2011-04-02)
The transactivation response element (TAR) DNA-binding protein-43 (TDP-43) is a nuclear protein that normally regulates transcription and splicing. Abnormal accumulation of insoluble inclusions containing TDP-43 has been recently reported in the affected tissues of amyotrophic lateral sclerosis (ALS) patients. Here
S Roy et al.
Antimicrobial agents and chemotherapy, 45(6), 1671-1681 (2001-05-17)
The microbicidal efficacies of two anionic surfactants, sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), were evaluated in cultured cells and in a murine model of herpes simplex type 2 (HSV-2) intravaginal infection. In vitro studies showed that SLS and LS

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