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Merck

H9903

Sigma-Aldrich

1-(Heptafluorobutyryl)imidazol

BioReagent, suitable for derivatization

Synonym(e):

1-Perfluorbutyryl-imidazol

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About This Item

Empirische Formel (Hill-System):
C7H3F7N2O
CAS-Nummer:
Molekulargewicht:
264.10
Beilstein:
4488026
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352005
PubChem Substanz-ID:
NACRES:
NA.32

Produktlinie

BioReagent

Qualitätsniveau

bp

158-163 °C (lit.)

Eignung

suitable for derivatization

Lagertemp.

−20°C

SMILES String

FC(F)(F)C(F)(F)C(F)(F)C(=O)n1ccnc1

InChI

1S/C7H3F7N2O/c8-5(9,6(10,11)7(12,13)14)4(17)16-2-1-15-3-16/h1-3H

InChIKey

MSYHGYDAVLDKCE-UHFFFAOYSA-N

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Allgemeine Beschreibung

1-(Heptafluorobutyryl)imidazole, also known as HFBI, is an acylating derivatization reagent. It is a mild amine-group derivatizing agent. HFBI doesn’t produce acidic by-products in reaction, and the unutilized reagent doesn’t damage the chromatographic process. Post derivatization reaction, the HFB (Heptafluorobutyryl) derivatives are analyzed chromatographically.

Anwendung

1-(Heptafluorobutyryl)imidazole is used as a derivatizing agent for analysing Sulphur mustard metabolites. It is suitable to study dispersive derivatization of degradation products.

Biochem./physiol. Wirkung

Mildes Amin-Gruppen Derivatisierungsreagens; nicht-saures Nebenprodukt verhindert Zersetzung und reduziert den GC-Säulen Abbau.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

170.6 °F - closed cup

Flammpunkt (°C)

77 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Meehir Palit et al.
Journal of chromatography. A, 1218(32), 5393-5400 (2011-07-09)
A new derivatization and extraction technique termed as dispersive derivatization liquid-liquid extraction (DDLLE) speeds up the analysis process by removing the requirement for drying of the sample. The derivatization process takes place at the interface between the analyte containing aqueous
A Fidder et al.
Archives of toxicology, 74(4-5), 207-214 (2000-08-26)
The development of a procedure for retrospective detection and quantitation of exposure to the arsenical dichloro(2-chlorovinyl)arsine (lewisite; L1) has been initiated. Upon incubation of human blood with [14C]L1 (20 nM-0.2 mM) in vitro, more than 90% of the total radioactivity
Zhiyong Nie et al.
Talanta, 85(2), 1154-1159 (2011-07-06)
The N-terminal valine adduct (HETE-Val) in globin is believed to behave as a long-lived biomarker after exposure to sulfur mustard (HD). Development of a highly sensitive method for monitoring HETE-Val, particularly at low HD exposure levels or for retrospective detection
Gas chromatographic determination of 2-ethylhexanol and 2-ethylhexanoic acid as derivatives suitable for electron-capture and nitrogen-phosphorus detection after single reaction with heptafluorobutyrylimidazole.
T Górski et al.
Journal of chromatography, 509(2), 383-389 (1990-06-22)
Xinxin Li et al.
Colloids and surfaces. B, Biointerfaces, 74(1), 370-374 (2009-09-01)
Patterning of neural stem cells (NSCs) is of great importance for its potential applications in the therapy of nerve injuries. Due to the critical requirements and the great difficulty in NSCs cultivation, developing new methods for NSCs patterning is very

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