G6392

L-Glutamin

γ-irradiated, BioXtra, suitable for cell culture

• Synonym(e): (S)-2,5-Diamino-5-oxopentansäure, L-Glutaminsäure-5-amid, Levoglutamid
• Lineare Formel: H₂NCOCH₂CH₂CH(NH₂)CO₂H
• CAS-Nummer: 56-85-9
• Molekulargewicht: 146.14
• Beilstein: 1723797
• EG-Nummer: 200-292-1
• MDL-Nummer: MFCD00008044
• UNSPSC-Code: 12352209
• eCl@ss: 32160406
• PubChem Substanz-ID: 24895254
• NACRES: NA.75

Eigenschaften

• Qualitätsniveau: 200
• Sterilität: γ-irradiated
• Produktlinie: BioXtra
• Form: powder
• Verpackung: vial of 0.292 g
• Methode(n): cell culture | mammalian: suitable
• Verunreinigungen: endotoxin, tested
• Farbe: white to faint yellow
• mp (Schmelzpunkt): 185 °C (dec.) (lit.)
• Löslichkeit: H₂O: 10 mL/vial, clear to slightly hazy
• SMILES String: N[C@@H](CCC(N)=O)C(O)=O
• InChI: 1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
• InChIKey: ZDXPYRJPNDTMRX-VKHMYHEASA-N
• Angaben zum Gen: rat ... Ggt1(116568)

Beschreibung

Anwendung

L-Glutamine has been used as a media supplement:

• for cochlear organotypic culturing
• in Iscove′s modified Dulbecco′s medium for HeLa cells culturing
• in Dulbecco′s modified Eagle′s medium for primary hepatocyte cell culturing

Biochem./physiol. Wirkung

Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signalling. It is also known to be associated with the inhibition of apoptosis.

L-glutamine is an essential amino acid that is a crucial component of culture media, and serves as a major energy source for cells in culture. Optimal cell performance usually requires supplementation of the medium with L-glutamine prior to use.

Glutaminsäure-Vorläufer und Metabolit; stimulierende Aminosäure

Verpackung

50 mL amber serum vial with rubber stopper.

Eignung

Qualified for use in cell culture applications, especially serum-free cell culture.

Rekonstituierung

Prepares a 200 mM solution when reconstituted to 10 mL with sterile water.

Sonstige Hinweise

The dipeptide L-Ala-LGln is frequently used in modern serum-free media formulations because it provides a more stable form of glutamine in vitro.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)