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G4878

Sigma-Aldrich

D-Glucosamine 6-phosphate sodium salt

≥98% (TLC)

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About This Item

Empirische Formel (Hill-System):
C6H14NO8P
CAS-Nummer:
70442-23-8
Molekulargewicht:
259.15
MDL-Nummer:
MFCD00069826
UNSPSC-Code:
12352201
PubChem Substanz-ID:
24895188
NACRES:
NA.25

Qualitätsniveau

200

Assay

≥98% (TLC)

Form

powder

Methode(n)

thin layer chromatography (TLC): suitable

Verunreinigungen

<12% water (Karl Fischer)

Farbe

white to off-white

Löslichkeit

water: 50 mg/mL, clear, colorless to light yellow

Kationenspuren

Na: <8.5%

Lagertemp.

−20°C

SMILES String

[Na].NC(C=O)C(O)C(O)C(O)COP(O)(O)=O

InChI

1S/C6H14NO8P.Na.H/c7-3(1-8)5(10)6(11)4(9)2-15-16(12,13)14;;/h1,3-6,9-11H,2,7H2,(H2,12,13,14);;

InChIKey

QSNQAUAPIDIXHB-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

Glucosamine 6-phosphate has been used to accelerate enzyme-cleavage of DNA plasmids.

Biochem./physiol. Wirkung

D-Glucosamine 6-phosphate, the natural form of glucosamine, is a monosaccharide produced during hexosamine biosynthesis pathway

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Adrian R Ferré-D'Amaré
Quarterly reviews of biophysics, 43(4), 423-447 (2010-09-09)
The glmS ribozyme is the first known example of a natural ribozyme that has evolved to require binding of an exogenous small molecule for activity. In Gram-positive bacteria, this RNA domain is part of the messenger RNA (mRNA) encoding the
Shota Atsumi et al.
Molecular systems biology, 6, 449-449 (2010-12-24)
Escherichia coli has been engineered to produce isobutanol, with titers reaching greater than the toxicity level. However, the specific effects of isobutanol on the cell have never been fully understood. Here, we aim to identify genotype-phenotype relationships in isobutanol response.
Pavel Banás et al.
The journal of physical chemistry. B, 114(26), 8701-8712 (2010-06-12)
The glmS catalytic riboswitch is part of the 5'-untranslated region of mRNAs encoding glucosamine-6-phosphate (GlcN6P) synthetase (glmS) in numerous gram-positive bacteria. Binding of the cofactor GlcN6P induces site-specific self-cleavage of the RNA. However, the detailed reaction mechanism as well as
Krista M Brooks et al.
Biochemistry, 50(13), 2424-2433 (2011-03-15)
The glmS ribozyme is a conserved riboswitch found in numerous Gram-positive bacteria and responds to the cellular concentrations of glucosamine 6-phosphate (GlcN6P). GlcN6P binding promotes site-specific self-cleavage in the 5' UTR of the glmS mRNA, resulting in downregulation of gene
Juliana L Sacoman et al.
Carbohydrate research, 346(14), 2294-2299 (2011-08-17)
The structural rationale, synthesis and evaluation of an inhibitor designed to block glucosamine synthesis by competitively inhibiting the action of glutamine: fructose-6-phosphate amidotransferase and subsequently reducing the transformation of any glucosamine-6-phosphate formed to UDP-N-acetylglucosamine are described. The inhibitor 2-acetamido-2,6-dideoxy-6-sulfo-D-glucose (D-glucosamine-6-sulfonate)
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