C8753

Cholesteryl arachidonate

≥95% (HPLC; detection at 205 nm), viscous liquid

• Synonym(e): 3β-Hydroxy-5-cholestene 3-arachidonate, 5-Cholesten-3β-ol 3-arachidonate, Cholesteryl eicosatetraenoate
• Empirische Formel (Hill-System): C₄₇H₇₆O₂
• CAS-Nummer: 604-34-2
• Molekulargewicht: 673.11
• MDL-Nummer: MFCD00056441
• UNSPSC-Code: 12352211
• PubChem Substanz-ID: 24893099
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥95% (HPLC; detection at 205 nm)
• Form: viscous liquid
• Farbe: clear
• Funktionelle Gruppe: ester
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: CCCCC\C=C\C\C=C\C\C=C\C\C=C\CCCC(=O)OC1CCC2(C)C3CCC4(C)C(CCC4C3CC=C2C1)C(C)CCCC(C)C
• InChI: 1S/C47H76O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-27-45(48)49-40-32-34-46(5)39(36-40)28-29-41-43-31-30-42(38(4)26-24-25-37(2)3)47(43,6)35-33-44(41)46/h11-12,14-15,17-18,20-21,28,37-38,40-44H,7-10,13,16,19,22-27,29-36H2,1-6H3/b12-11+,15-14+,18-17+,21-20+
• InChIKey: IMXSFYNMSOULQS-SXXSVFILSA-N

Beschreibung

Anwendung

Cholesteryl arachidoante was oxidized and used to study the biological effects.

Biochem./physiol. Wirkung

Cholesteryl arachidonate is a cholesterol ester found associated with the neutral core of low density lipoprotein. Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters. The enzyme acid cholesteryl ester hydrolase is responsible for the hydrolysis of cholesteryl esters; a defective enzyme can result in the formation of atherosclerotic lesions in humans.

Angaben zur Herstellung

Cholesteryl arachidonate is a clear, colorless viscous liquid in chloroform.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves