C8011

Chelidamsäure Hydrat

≥95%, powder

• Synonym(e): 1,4-Dihydro-4-oxo-2,6-pyridindicarbonsäure Hydrat, 4-Hydroxy-pyridin-2,6-dicarbonsäure
• Empirische Formel (Hill-System): C₇H₅NO₅ · xH₂O
• CAS-Nummer: 138-60-3
• Molekulargewicht: 183.12 (anhydrous basis)
• Beilstein: 476229
• EG-Nummer: 205-335-8
• MDL-Nummer: MFCD03818117
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24278338
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 200
• Assay: ≥95%
• Form: powder
• Farbe: brown
• mp (Schmelzpunkt): 267 °C (dec.) (lit.)
• Löslichkeit: 1 M NH4OH: 50 mg/mL, clear to slightly hazy
• SMILES String: O.OC(=O)C1=CC(=O)C=C(N1)C(O)=O
• InChI: 1S/C7H5NO5.H2O/c9-3-1-4(6(10)11)8-5(2-3)7(12)13;/h1-2H,(H,8,9)(H,10,11)(H,12,13);1H2
• InChIKey: SNGPHFVJWBKEDG-UHFFFAOYSA-N

Beschreibung

Anwendung

Chelidamic acid hydrate has been used in eluent solution as a complexing additive in high-performance chelation ion chromatography (HPCIC) for speciation of iron. It has also been used as an organic ligand for the polyoxometalate (POM)-based lanthanoid hybrid compounds.

Biochem./physiol. Wirkung

Chelidamic acid (CDA), a hydroxylated derivative of 2,6-pyridine-dicarboxylic acid (DPA), is a trianionic chelating agent.

Among the most potent of the tested "conformationally restricted glutamate analogs" as an inhibitor of glutamate decarboxylase.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves