A0580

Arachidonylethanolamide

≥97.0% (TLC), oil

• Synonym(e): Anandamide (20:4, n-6), AEA, Anandamide, Arachidonic acid N-(hydroxyethyl)amide
• Empirische Formel (Hill-System): C₂₂H₃₇NO₂
• CAS-Nummer: 94421-68-8
• Molekulargewicht: 347.53
• MDL-Nummer: MFCD00153766
• UNSPSC-Code: 12352211
• PubChem Substanz-ID: 24890438
• NACRES: NA.25

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥97.0% (TLC)
• Form: oil
• Arzneimittelkontrolle: regulated under CDSA - not available from Sigma-Aldrich Canada
• Farbe: colorless to light yellow
• Löslichkeit: ethanol: soluble
• Dichte: 0.92 g/mL at 25 °C (lit.)
• Lipid-Typ: omega FAs
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCCO
• InChI: 1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
• InChIKey: LGEQQWMQCRIYKG-DOFZRALJSA-N
• Angaben zum Gen: rat ... Cnr1(25248)

Beschreibung

Anwendung

• Interactions Between Endocannabinoid and Endogenous Opioid Systems Prospectively Influence Postoperative Opioid Use in Pregnant Patients Undergoing Cesarean Delivery: Investigates Arachidonylethanolamide′s interactions with opioid systems, providing insights that could lead to better management of postoperative pain and opioid use (Stone et al., 2024).

Biochem./physiol. Wirkung

An arachidonic acid derivative that is an endogenous ligand for the CB cannabinoid receptor and for the VR1 vanilloid receptor. Inhibits calcium currents in neuroblastomas and neurons. Activates the MAP kinase signaling pathway. Inhibits proliferation and induces apoptosis of lymphocytes and human breast cancer cells.

Vorsicht

Protect from light and moisture.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)