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Merck

B3916

Supelco

Boldin

analytical standard

Synonym(e):

2,9-Dihydroxy-1,10-dimethoxy-aporphin

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About This Item

Empirische Formel (Hill-System):
C19H21NO4
CAS-Nummer:
Molekulargewicht:
327.37
Beilstein:
94036
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Biologische Quelle

plant (Peumus boldus molina)

Qualitätsniveau

Qualität

analytical standard

Assay

≥98% (TLC)

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Verunreinigungen

≤1% isopropanol

mp (Schmelzpunkt)

157-164  °C

Löslichkeit

ethanol: 50 mg/mL

Anwendung(en)

food and beverages
forensics and toxicology
veterinary

Format

neat

Lagertemp.

room temp

SMILES String

COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c-2c34)cc1O

InChI

1S/C19H21NO4/c1-20-5-4-10-7-15(22)19(24-3)18-12-9-16(23-2)14(21)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1

InChIKey

LZJRNLRASBVRRX-ZDUSSCGKSA-N

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Allgemeine Beschreibung

Boldine is an aporphine alkaloid isolated from Boldo tree and other plant species. It is a free radical scavenger with anti-inflammatory activity while exhibiting other pharmacological effects such as antidiabetic, antiplatelet aggregation, antipyretic, antinociceptive, antiatherogenic, hepatoprotective and endothelium-protective activity.

Anwendung

Boldine may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical preparations using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Mat Ropi Mukhtar et al.
Molecules (Basel, Switzerland), 14(3), 1227-1233 (2009-03-28)
The stem bark of Phoebe grandis afforded one new oxoproaporphine; (-)-grandine A (1), along with six known isoquinoline alkaloids: (-)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete 1H- and
Eduardo L Konrath et al.
Neurotoxicology, 29(6), 1136-1140 (2008-07-02)
Boldine is one of the most potent natural antioxidants and displays some important pharmacological activities, such as cytoprotective and anti-inflammatory activities, which may arise from its free radical scavenging properties. Given that the pathogenesis of brain ischemia/reperfusion has been associated
Advances in development of dopaminergic aporphinoids.
Ao Zhang et al.
Journal of medicinal chemistry, 50(2), 171-181 (2007-01-19)
HPLC analysis of boldine in pharmaceuticals
Orsi D.D, et al.
Chromatographia, 44(11-12), 610-622 (1997)
María Eliana Hidalgo et al.
Journal of photochemistry and photobiology. B, Biology, 80(1), 65-69 (2005-06-21)
Boldine hydrochloride was more photounstable than boldine after irradiation with UVB (lambda = 300 nm). However, photoconsumption quantum yields, for glaucine hydrochloride (6.5 x 10(-2)) and boldine hydrochloride (6.7 x 10(-2)) in air, were quite similar. The photolysis was oxygen

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