235989

Brij^® L4

average M_n ~362

• Synonym(e): Polyethylenglykol-dodecylether, Polyoxyethylen(4)-laurylether
• Lineare Formel: (C₂₀H₄₂O₅)_n
• CAS-Nummer: 9002-92-0
• MDL-Nummer: MFCD00043063
• UNSPSC-Code: 12161900
• PubChem Substanz-ID: 24854130
• NACRES: NA.21

Eigenschaften

• Beschreibung: non-ionic
• Qualitätsniveau: 200
• Mol-Gew.: average M_n ~362
• Brechungsindex: n20/D 1.451 (lit.)
• Dichte: 0.95 g/mL at 25 °C (lit.)
• HLB: 9
• SMILES String: CCCCCCCCCCCCOCCOCCOCCOCCO
• InChI: 1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3
• InChIKey: WPMWEFXCIYCJSA-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Brij^® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.

Anwendung

Brij^® L4 has been used:

• as a surfactant for the synthesis of copper(I) oxide (Cu₂O) spherical nanoparticles using a microemulsion technique
• as a non-ionic surfactant for preparing reverse micelles to synthesize Pt₃Co alloy nanoparticles
• as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel

Biochem./physiol. Wirkung

Brij^® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.

Rechtliche Hinweise

Brij is a registered trademark of Croda International PLC

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H411
• P-Sätze: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves