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Merck

P4019

Sigma-Aldrich

Brij® S20

Synonym(e):

Polyethylenglykol-octadecylether, Polyoxyethylen 200-stearyl-ether

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About This Item

Lineare Formel:
C18H37(OCH2CH2)nOH, n~20
CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12162002
PubChem Substanz-ID:
NACRES:
NA.23

Form

solid

Qualitätsniveau

mp (Schmelzpunkt)

44-46 °C (lit.)

HLB

15

SMILES String

CCCCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3

InChIKey

PSEGVHKUPXNGGJ-UHFFFAOYSA-N

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Allgemeine Beschreibung

Brij® S20 is a surfactant that belongs to the class of polyoxyethylene ethers. It is majorly used in pharmaceutical applications to improve the solubility of the drugs. It can also be grafted on a variety of surfaces to enhance the intracellular uptake of dyes.

Anwendung


  • Nanostructured lipid carriers for oral delivery of silymarin: Improving its absorption and in vivo efficacy in type 2 diabetes and metabolic syndrome model.: This study utilizes Brij® S20 to develop nanostructured lipid carriers for oral delivery of silymarin. The findings demonstrate enhanced absorption and efficacy of silymarin in treating type 2 diabetes and metabolic syndrome, highlighting the potential of Brij® S20 in improving drug delivery systems. (Piazzini et al., 2019).

  • Water-stable all-biodegradable microparticles in nanofibers by electrospinning of aqueous dispersions for biotechnical plant protection.: The study uses Brij® S20 to create water-stable, biodegradable microparticles in nanofibers through electrospinning. These microparticles are designed for biotechnical plant protection, demonstrating the potential of Brij® S20 in agricultural biotechnology. (Bansal et al., 2012).


Rechtliche Hinweise

Brij is a registered trademark of Croda International PLC

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Preisangaben

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Nanostructured lipid carriers as promising delivery systems for plant extracts: The case of silymarin
Piazzini V, et al.
Applied Sciences, 8(7), 1163-1163 (2018)
Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations
Xiong W, et al.
Carbohydrate Polymers, 204, 89-96 (2019)
Wei Xiong et al.
International journal of nanomedicine, 13, 3781-3793 (2018-07-11)
Berberine (BBR) is a plant-derived benzylisoquinoline alkaloid and has been demonstrated to be a potential treatment for various chronic diseases. The poor water solubility and P-glycoprotein (Pgp)-mediated drug efflux are the main challenges for its further application in a clinical
J P Lens et al.
Journal of biomaterials science. Polymer edition, 8(12), 963-982 (1997-01-01)
Alkyl-poly(ethylene oxide) (PEO) surfactants containing a terminal hydroxyl, sulfate, or carboxylate group were grafted at the surface of poly(ethylene) (PE) samples to improve their blood compatibility. Grafting was achieved by immobilizing PEO surfactants on PE using an argon plasma treatment.
Y C Lee et al.
Journal of pharmaceutical sciences, 86(4), 430-433 (1997-04-01)
An ocular insert is developed for the controlled systemic delivery of insulin. Commercially available Gelfoam absorbable gelatin sponge, USP, is used in the fabrication of the ocular insert in the form of a matrix system. Two eyedrop formulations and 13

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