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Merck
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Wichtige Dokumente

MAB2078Z

Sigma-Aldrich

Anti-Integrin α9β1 Antibody, clone Y9A2, azide free

clone Y9A2, Chemicon®, from mouse

Synonym(e):

MAB2078

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Klon:
Y9A2, monoclonal
application:
FACS
IP
Speziesreaktivität:
human, guinea pig
Methode(n):
flow cytometry: suitable
immunoprecipitation (IP): suitable
citations:
15
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

Y9A2, monoclonal

Speziesreaktivität

human, guinea pig

Darf nicht reagieren mit

rat

Hersteller/Markenname

Chemicon®

Methode(n)

flow cytometry: suitable
immunoprecipitation (IP): suitable

Isotyp

IgG1

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Dieser Artikel
MAB2074ZMAB1953ZMAB2059Z
clone

Y9A2, monoclonal

clone

E7P6, monoclonal

clone

P3G8, monoclonal

clone

ASC-8, monoclonal

species reactivity

human, guinea pig

species reactivity

human

species reactivity

human

species reactivity

human

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

Gene Information

human ... ITGA9(3680)

Gene Information

human ... ITGAV(3685)

Gene Information

human ... ITGAV(3685)

Gene Information

human ... ITGB4(3691)

isotype

IgG1

isotype

IgG1

isotype

IgG1

isotype

IgG1κ

Spezifität

Reactive with human and guinea pig alpha9beta1.

Immunogen

Murine L cells transfected with human alpha9.

Anwendung

Research Category
Zellstruktur
Research Sub Category
Integrine
Detect Integrin α9β1 using this Anti-Integrin α9β1 Antibody, clone Y9A2, azide free validated for use in FC & IP.
Immunoprecipitation

FACS Analysis

Function blocking: 100% inhibition of alpha9beta1-mediated adhesion to the third fibronectin type III repeat in tenascin at <10 μg/mL.

Not effective for immunohistochemistry, immunocytochemistry or western blot.

Optimal working dilutions must be determined by end user.

Physikalische Form

Protein A purified
Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.

Lagerung und Haltbarkeit

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hinweis zur Analyse

Control
Integrin alpha9beta1 positive tissues include basal keratinocytes, hepatocytes, muscle (smooth and skeletal), and airway epithelium.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


  • Analysenzertifikate (COA)

    Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

    Besitzen Sie dieses Produkt bereits?

    In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

    Die Dokumentenbibliothek aufrufen

    Patrick M Lelliott et al.
    ImmunoHorizons, 6(2), 170-183 (2022-02-24)
    Anti-neutrophil cytoplasmic Ab (ANCA)-associated vasculitis (AAV) is a life-threatening condition characterized by improper activation of neutrophils and the release of neutrophil extracellular traps (NETs) in small vessels. This study aimed to explain the role of NETs in AAV pathogenesis by
    A V Timoshenko et al.
    British journal of cancer, 97(8), 1090-1098 (2007-10-04)
    Vascular endothelial growth factor C (VEGF-C) is a lymphangiogenic factor over-expressed in highly metastatic, cyclooxygenase (COX)-2 expressing breast cancer cells. We tested the hypothesis that tumour-derived VEGF-C may play an autocrine role in metastasis by promoting cellular motility through one
    Jochen Grassinger et al.
    Blood, 114(1), 49-59 (2009-05-07)
    Osteopontin (OPN), a multifunctional acidic glycoprotein, expressed by osteoblasts within the endosteal region of the bone marrow (BM) suppresses the proliferation of hemopoietic stem and progenitor cells and also regulates their lodgment within the BM after transplantation. Herein we demonstrate
    Whitney M Longmate et al.
    The Journal of cell biology, 216(5), 1473-1488 (2017-04-19)
    Development of wound therapies is hindered by poor understanding of combinatorial integrin function in the epidermis. In this study, we generated mice with epidermis-specific deletion of α3β1, α9β1, or both integrins as well as keratinocyte lines expressing these integrin combinations.
    Koichi Nishino et al.
    Scientific reports, 11(1), 8406-8406 (2021-04-18)
    Lymphangioleiomyomatosis (LAM) is a rare pulmonary disease characterised by the proliferation of smooth muscle-like cells (LAM cells), and an abundance of lymphatic vessels in LAM lesions. Studies reported that vascular endothelial growth factor-D (VEGF-D) secreted by LAM cells contributes to

    Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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