857231P

C18:1 Cyclic LPA

1-O-(9Z-octadecenyl)-sn-glycero-2,3-cyclic-phosphate (ammonium salt), powder

• Synonym(e): 1-O-octadecenyl-sn-glycero-2,3-cyclic-phosphate (ammonium salt); AGP 18:1
• Empirische Formel (Hill-System): C₂₁H₄₄NO₅P
• CAS-Nummer: 799268-69-2
• Molekulargewicht: 421.55
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 1 mg (857231P-1mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 857231P
• Lipid-Typ: cardiolipins; phospholipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: CCCCCCCC/C=C\CCCCCCCCOC[C@@H]1COP(O1)([O-])=O.[NH4+]
• InChI: 1S/C21H41O5P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24-19-21-20-25-27(22,23)26-21;/h9-10,21H,2-8,11-20H2,1H3,(H,22,23);1H3/b10-9-;/t21-;/m1./s1
• InChIKey: OQYRMQWRTNWOER-WBIWQBECSA-N

Beschreibung

Allgemeine Beschreibung

Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). The sn-2 hydroxy group of CPA forms a 5-membered ring with the sn-3 phosphate. cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle,induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells.
Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations.

Verpackung

5 mL Amber Glass Screw Cap Vial (857231P-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3