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5-Amino-uracil
98%
Synonym(e):
5-Amino-2,4-dihydroxy-pyrimidin (5-2,6), 5-Amino-2,4-pyrimidindiol
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About This Item
Empirische Formel (Hill-System):
C4H5N3O2
CAS-Nummer:
Molekulargewicht:
127.10
Beilstein:
127250
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
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Qualitätsniveau
Assay
98%
Form
powder
mp (Schmelzpunkt)
>300 °C (lit.)
SMILES String
NC1=CNC(=O)NC1=O
InChI
1S/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9)
InChIKey
BISHACNKZIBDFM-UHFFFAOYSA-N
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Paulina Spisz et al.
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Hypoxia-a hallmark of solid tumors-dramatically impairs radiotherapy, one of the most common anticancer modalities. The adverse effect of the low-oxygen state can be eliminated by the concomitant use of a hypoxic cell radiosensitizer. In the present paper, we show that
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In this investigation, 2-cyano-N-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl) acetamide (3) reacts with dimethylformamide dimethyl acetal (DMF-DMA) to afford the corresponding (E)- 2-cyano-3-(dimethylamino)-N-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylam-ide (4) utilizing microwave irradiation. The condensation reactions of acrylamide derivative 4 with hydrazine derivatives obtain pyrazole derivatives 6a and 6b; respectively. The
Recovery from the 5-AU induced blockage in interphase: evidence for differential recovery.
D Davidson
Cytologia, 47(3-4), 545-553 (1982-12-01)
M H Navarrete et al.
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Meristematic cells from Allium cepa L roots can attain a steady-state of growth at both 15 and 25 degrees C in the presence of drugs, hydroxyurea and 5-amino-uracil, which reduce the rate of DNA synthesis. These drugs, at used concentrations
Francisco Hueso-Ureña et al.
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The synthesis, spectroscopic (IR, 1H and 13C NMR, UV-Vis-NIR, EPR), magnetic measurements and biological studies of a number of complexes of Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Au(III) and Hg(II) of the Schiff base derived from the 1:2 condensation of 2,6-diformyl-4-methylphenol
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