337358

4-Iod-2-methylphenol

97%

• Synonym(e): 4-Iod-o-kresol
• Lineare Formel: IC₆H₃(CH₃)OH
• CAS-Nummer: 60577-30-2
• Molekulargewicht: 234.03
• MDL-Nummer: MFCD00075092
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24860475
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• bp: 105-110 °C/2 mmHg (lit.)
• mp (Schmelzpunkt): 67-68 °C (lit.)
• Funktionelle Gruppe: iodo
• SMILES String: Cc1cc(I)ccc1O
• InChI: 1S/C7H7IO/c1-5-4-6(8)2-3-7(5)9/h2-4,9H,1H3
• InChIKey: WSBDSSKIWDFOBQ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

4-Iodo-2-methylphenol was prepared by direct iodination of 2-methylphenol in aqueous alcohol solvents by the action of a reagent prepared in situ from sodium hypochlorite and sodium iodide.

Anwendung

4-Iodo-2-methylphenol was used as starting reagent in the synthesis of an agonist for the peroxisome proliferator-activated receptor δ (PPARδ) GW501516, a potential antiobesity drug.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves