238902

2-(Trimethylsilyl)-ethoxymethylchlorid

technical grade

• Synonym(e): (2-Chlormethoxyethyl)-trimethylsilan, Chlormethyl-2-trimethylsilylethylether, SEM-Cl, SEM-chlorid
• Lineare Formel: (CH₃)₃SiCH₂CH₂OCH₂Cl
• CAS-Nummer: 76513-69-4
• Molekulargewicht: 166.72
• Beilstein: 3587289
• EG-Nummer: 278-483-4
• MDL-Nummer: MFCD00009919
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 24854351
• NACRES: NA.22

Eigenschaften

• Qualität: technical grade
• Qualitätsniveau: 100
• Form: liquid
• Brechungsindex: n20/D 1.435 (lit.)
• bp: 170-172 °C (lit.); 57-59 °C/8 mmHg (lit.)
• Dichte: 0.942 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro; ether
• Lagertemp.: −20°C
• SMILES String: C[Si](C)(C)CCOCCl
• InChI: 1S/C6H15ClOSi/c1-9(2,3)5-4-8-6-7/h4-6H2,1-3H3
• InChIKey: BPXKZEMBEZGUAH-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.

Anwendung

Phenol protecting group in the synthesis of laterifluorones.

Used to prepare a SEM-ether which was, in turn, removed with BBr₃ and cyclized to a benzo-oxapane.

Leistungsmerkmale und Vorteile

Convenient hydroxyl-protecting reagent. SEM-ethers are stable over a wide pH range, and can be selectively cleaved with fluoride ion under mild aprotic conditions.

Sicherheitshinweise

• Piktogramme: GHS02,GHS05
• Signalwort: Danger
• H-Sätze: H226,H314
• P-Sätze: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Flam. Liq. 3 - Skin Corr. 1B
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 114.8 °F - closed cup
• Flammpunkt (°C): 46 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter