142077

Chlorameisensäure-2,2,2-trichlorethylester

98%

• Synonym(e): 2,2,2-Trichlorethyl-chlorformiat
• Lineare Formel: ClCOOCH₂CCl₃
• CAS-Nummer: 17341-93-4
• Molekulargewicht: 211.86
• Beilstein: 970619
• EG-Nummer: 241-363-7
• MDL-Nummer: MFCD00000810
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24848380
• NACRES: NA.22

Eigenschaften

• Dampfdruck: 0.06 psi ( 20 °C)
• Qualitätsniveau: 200
• Assay: 98%
• Form: liquid
• Brechungsindex: n20/D 1.471 (lit.)
• bp: 171-172 °C (lit.)
• Dichte: 1.539 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro
• Lagertemp.: 2-8°C
• SMILES String: ClC(=O)OCC(Cl)(Cl)Cl
• InChI: 1S/C3H2Cl4O2/c4-2(8)9-1-3(5,6)7/h1H2
• InChIKey: LJCZNYWLQZZIOS-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2,2,2-Trichloroethyl chloroformate (TrocCl) serves as a versatile reagent used for selective acylation and dealkylation in organic synthesis. It is used in regio, chemo, and stereoselective synthesis.

Anwendung

Protecting reagent for aliphatic and aromatic hydroxyl and amino groups.

• 2,2,2-Trichloroethyl chloroformate was used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples.
• It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester.
• It was used as reagent during N-demethylation of dextromethorphan.
• It was used as protecting reagent for aliphatic and aromatic hydroxyl and amino groups.

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H314,H331
• P-Sätze: P280 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338 + P310
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter