210145

2,2-Dimethyl-1,3-dioxan-4,6-dion

98%

• Synonym(e): Malonsäure-cycl.-isopropylidenester, cycl.-Isopropyliden-malonat, ‘Meldrum’s Säure’
• Empirische Formel (Hill-System): C₆H₈O₄
• CAS-Nummer: 2033-24-1
• Molekulargewicht: 144.13
• Beilstein: 117310
• EG-Nummer: 217-992-8
• MDL-Nummer: MFCD00006638
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24852618
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 98%
• Form: solid
• mp (Schmelzpunkt): 92-96 °C (lit.)
• Löslichkeit: dioxane: soluble 5%, clear to very slightly hazy, colorless to faintly yellow
• Funktionelle Gruppe: ester; ketal
• Lagertemp.: 2-8°C
• SMILES String: CC1(C)OC(=O)CC(=O)O1
• InChI: 1S/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H3
• InChIKey: GXHFUVWIGNLZSC-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Benzyl substituted Meldrum′s acids, available via aldol condensation and reduction with triethylammonium formate, were used to form indanones upon hydrolysis, loss of CO₂, and Friedel-Crafts cyclization with chlorosulfonic acid. Knoevenagel condensations between aldehydes and Meldrum′s acid are accelerated in ionic liquids.

Anwendung

Used in an efficient synthesis of isofraxidin.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)