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122564

Sigma-Aldrich

Mechlorethamin -hydrochlorid

98%

Synonym(e):

2-Chlor-N-(2-chlorethyl)-N-methylethanamin, N-Methylbis-(2-chlorethyl)-amin -hydrochlorid, Bis-(2-chlorethyl)-methylamin, Stickstofflost

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About This Item

Lineare Formel:
(ClCH2CH2)2NCH3·HCl
CAS-Nummer:
55-86-7
Molekulargewicht:
192.51
EG-Nummer:
200-246-0
MDL-Nummer:
MFCD00012517
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24847496
NACRES:
NA.22

Qualitätsniveau

100

Assay

98%

Form

solid

mp (Schmelzpunkt)

108-111 °C (lit.)

Löslichkeit

H2O: very soluble
alcohol: soluble

Funktionelle Gruppe

amine
chloro

SMILES String

Cl.CN(CCCl)CCCl

InChI

1S/C5H11Cl2N.ClH/c1-8(4-2-6)5-3-7;/h2-5H2,1H3;1H

InChIKey

QZIQJVCYUQZDIR-UHFFFAOYSA-N

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Anwendung

Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.

Biochem./physiol. Wirkung

Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 1 Dermal - Acute Tox. 2 Oral - Carc. 1B - Eye Dam. 1 - Muta. 1B - Repr. 1B - Skin Corr. 1B

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Analysenzertifikate (COA)

Lot/Batch Number
MKCK7776
MKBW4481V
41796PJ
38697LJ
07118JJ

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