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222941

Sigma-Aldrich

4-Iodobenzenesulfonyl chloride

95%

Synonym(s):

Pipsyl chloride

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About This Item

Linear Formula:
IC6H4SO2Cl
CAS Number:
Molecular Weight:
302.52
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

mp

80-82 °C (lit.)

solubility

ethanol: soluble 100 mg/mL, clear to slightly hazy, colorless to yellow

functional group

iodo

SMILES string

ClS(=O)(=O)c1ccc(I)cc1

InChI

1S/C6H4ClIO2S/c7-11(9,10)6-3-1-5(8)2-4-6/h1-4H

InChI key

POXFXTSTVWDWIR-UHFFFAOYSA-N

General description

The reaction of 4-iodobenzenesulfonyl chloride (pipsyl chloride) with peptides under various conditions has been studied.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J C Fletcher
The Biochemical journal, 102(3), 815-824 (1967-03-01)
1. A system of separation using buffered Celite columns is described that enables the pipsyl derivatives of most of the common amino acids to be separated. 2. The reaction of pipsyl chloride with several amino acids not included in previous
Circular dichroism study of thyroxine-binding globulin derivatized with p-iodophenylsulfonyl chloride.
J S Siegel et al.
The International journal of biochemistry, 16(5), 575-577 (1984-01-01)
Franky Ka-Wah Hau et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 22(11), 3738-3749 (2016-02-03)
A series of mononuclear and dinuclear platinum(II) terpyridine complexes with amide-, sulfonamide-, and urea-containing ligands (1-9) has been successfully designed and synthesized, and their photophysical and anion-binding properties have been studied. The anion-binding properties of the complexes were studied by

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