107840

2,2,2-Trifluoroacetophenone

99%

• Synonym(s): α,α,α-Trifluoroacetophenone, Phenyl trifluoromethyl ketone
• Linear Formula: CF₃COC₆H₅
• CAS Number: 434-45-7
• Molecular Weight: 174.12
• Beilstein: 1866286
• EC Number: 207-103-1
• MDL number: MFCD00000420
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846784
• NACRES: NA.22

Properties

• Assay: 99%
• refractive index: n20/D 1.458 (lit.)
• bp: 165-166 °C (lit.); 46-48 °C/14 mmHg (lit.)
• density: 1.24 g/mL at 25 °C (lit.)
• functional group: fluoro; ketone; phenyl
• SMILES string: FC(F)(F)C(=O)c1ccccc1
• InChI: 1S/C8H5F3O/c9-8(10,11)7(12)6-4-2-1-3-5-6/h1-5H
• InChI key: KZJRKRQSDZGHEC-UHFFFAOYSA-N

Description

General description

2,2,2-Trifluoroacetophenone is the starting material for the synthesis of f 3-trifluoromethyl-3-phenyldiazirine. It undergoes asymmetric reduction with optically active Grignard reagent to form 2,2,2-trifluoro-1-phenylethanol. It undergoes condensation with biphenyl, terphenyl, a mixture of biphenyl with terphenyl, phenyl ether and diphenoxybenzophenone to form new aromatic 3F polymers.

2,2,2-trifluoroacetophenone is used as an organocatalyst for the oxidation of tertiary amines and azines to N-oxidesalkenes.

Application

2,2,2-Trifluoroacetophenone was used in the synthesis of new fluorinated polymers, having high average molecular weight, high thermal stability and good film-forming properties.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H315,H319,H335
• Precautionary Statements: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 105.8 °F - closed cup
• Flash Point(C): 41 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves