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Merck
모든 사진(1)

주요 문서

V4512

Sigma-Aldrich

Vascular Endothelial Growth Factor from mouse

≥98% (SDS-PAGE), recombinant, expressed in E. coli, powder, suitable for cell culture

동의어(들):

mVEGF, VEGF

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크기 선택

10 μG
₩829,458
50 μG
₩1,857,653

₩829,458


구입 가능 여부는 고객센터에 문의하십시오.


크기 선택

보기 변경
10 μG
₩829,458
50 μG
₩1,857,653

About This Item

MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.77

₩829,458


구입 가능 여부는 고객센터에 문의하십시오.

제품명

Vascular Endothelial Growth Factor from mouse, VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture

생물학적 소스

mouse

Quality Level

재조합

expressed in E. coli

분석

≥98% (SDS-PAGE)

양식

powder

효능

≤10 ng/mL

품질

endotoxin tested

분자량

protein 39 kDa

포장

pkg of 10 μg
pkg of 50 μg

저장 조건

avoid repeated freeze/thaw cycles

기술

cell culture | mammalian: suitable

불순물

<1 EU/μg

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

mouse ... VEGFA(22339)

일반 설명

Vascular endothelial growth factor is also known as VPF, VEGF and MVCD1. It is secreted from endothelial cells and pericytes in response to hypoxia. It helps in inducing angiogenesis and microvascular hyperpermeability. VEGF levels are associated with vasculitic neuropathy and may be used to predict this disease.[1] It may also act as a marker in the development and progression of early precancerous lesions of oesophagus.[2]

애플리케이션

Vascular endothelial growth factor (VEGF) supports development of new blood vessels during embryonic development and after vascular injury.Vascular endothelial growth factor from mouse was used for ELISA[3] and in matrigel plugs (matrigel was supplemented with VEGF).[4]

기타 정보

Homodimeric protein consisting of two 165 amino acid polypeptide chains of mouse VEGF.

물리적 형태

Lyophilized from a 0.2 μm filtered buffered solution.

분석 메모

The biological activity is measured by the ability to stimulate 3H-thymidine incorporation in human umbilical vein endothelial cells (HUVEC) and bovine aortic endothelial cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Katsuhisa Tashiro et al.
Stem cells and development, 23(18), 2202-2210 (2013-12-19)
Vascular endothelial growth factor (VEGF) is reported to exhibit potent hematopoietic stem/progenitor cell (HSPC) mobilization activity. However, the detailed mechanisms of HSPC mobilization by VEGF have not been examined. In this study, we investigated the effect of VEGF on bone
Asieh Golozar et al.
European journal of cancer (Oxford, England : 1990), 50(16), 2855-2865 (2014-08-31)
Mechanisms involved in wound healing play some role in carcinogenesis in multiple organs, likely by creating a chronic inflammatory milieu. This study sought to assess the role of genetic markers in selected inflammation-related genes involved in wound healing (interleukin (IL)-1a
Farzana Sharmin et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 35(5), 1086-1095 (2016-05-08)
Autografts have been shown to stimulate osteogenesis, osteoclastogenesis, and angiogenesis, and subsequent rapid graft incorporation. Large structural allografts, however, suffer from limited new bone formation and remodeling, both of which are directly associated with clinical failure due to non-unions, late
Benjamin B Bartelle et al.
Circulation research, 110(7), 938-947 (2012-03-01)
The formation and maintenance of a functional vasculature is essential for normal embryonic development, and genetic changes that affect the vasculature underlie pathogenesis in many human diseases. In vivo imaging in mouse models is required to understand the full complexity
Jafar Rezaie et al.
Journal of cellular biochemistry, 119(1), 524-535 (2017-06-14)
This experiment investigated the impact of serum from patients with type 2 diabetes mellitus on the angiogenic behavior of human mesenchymal stem cells in vitro. Changes in the level of Ang-1, Ang-2, cell migration, and trans-differentiation into pericytes and endothelial

문서

VEGF-A stimulates blood vessel growth via endothelial cell proliferation, migration, and survival during embryonic development.

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