SRP3247
M-CSF from rat
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
동의어(들):
CSF-1, MGI-IM, Macrophage Colony Stimulating Factor
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크기 선택
10 μG
₩572,054
₩572,054
구입 가능 여부는 고객센터에 문의하십시오.
모든 사진(1)
크기 선택
보기 변경
10 μG
₩572,054
About This Item
UNSPSC 코드:
12352202
NACRES:
NA.32
₩572,054
구입 가능 여부는 고객센터에 문의하십시오.
추천 제품
생물학적 소스
rat
재조합
expressed in E. coli
분석
≥98% (HPLC)
≥98% (SDS-PAGE)
양식
lyophilized
효능
≤5.0 ng/mL ED50
분자량
18.1 kDa
포장
pkg of 10 μg
기술
cell culture | mammalian: suitable
불순물
<0.2 EU/μg endotoxin, tested
색상
white to off-white
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
rat ... CSF1(78965)
일반 설명
Macrophage colony stimulating factor (M-CSF) is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts.The gene encoding this protein is localized on rat chromosome 2q34.[1][2] The human protein is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant rat M-CSF is a 36.2kDa homodimeric protein containing two 155 amino acid polypeptide subunits.
생화학적/생리학적 작용
Macrophage colony stimulating factor (M-CSF) is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility.[1][3] M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation.
서열
MEVSEHCSHM IGNGHLQILQ QLIDSQMETA CLIEYKFVDQ EQLDDPVCYL KKAFVLVQVI IEETMRFKDN TPNANATERL QELSMKLNSC FIKDYKEQNE ACVQTYKESP LRLLEKIKNF FNETKNFLEK DWNIFSKNCN DSLAKCSSRD VVTKP
물리적 형태
Lyophilized from 5 mM Sodium Phosphate, pH 7.5.
재구성
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts.
Paulus P
Cancer Research, 66(8), 4349-4356 (2006)
Circulating colony stimulating factor-1 and breast cancer risk.
Tamimi RM
Cancer Research, 68(1), 18-21 (2008)
The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat Csf1 gene: Evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossification.
Van Wesenbeeck L
Proceedings of the National Academy of Sciences of the USA, 99(22), 14303-14308 (2002)
Stanley, E.R., et al.
The Cytokine Handbook, 387-418 (1994)
Jiali Wang et al.
Biomaterials, 268, 120576-120576 (2020-12-04)
Periosteum can improve tendon-bone healing when applied to wrap the tendon graft in both animal studies and clinical trials. As magnesium (Mg) ions can significantly elevate the levels of relevant cytokines involving in the osteogenic differentiation of periosteum-derived stem cells
활성 필터
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