ML303 is a potent inhibitor (IC50 = 155 nM) of the influenza viral protien NS1. NS1 enhances virulence by inhibiting host cell immune responses, including the expression of IFN-b, and regulating synthesis, splicing and translation of viral RNA.
ML303 is a potent inhibitor of the influenza viral protien NS1.
International journal of molecular sciences, 21(4) (2020-02-27)
Influenza (flu) is a contagious viral disease, which targets the human respiratory tract and spreads throughout the world each year. Every year, influenza infects around 10% of the world population and between 290,000 and 650,000 people die from it according
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