추천 제품
분석
≥98% (HPLC)
양식
powder
저장 조건
desiccated
색상
white to tan
solubility
DMSO: ≥5 mg/mL at 60 °C
저장 온도
2-8°C
SMILES string
OC(=O)C=CC(=O)c1ccc(cc1)CCCCCCCCCCCCCCCCCC
InChI
1S/C28H44O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-25-19-21-26(22-20-25)27(29)23-24-28(30)31/h19-24H,2-18H2,1H3,(H,30,31)
InChI key
ZBESASFHIWDSCJ-UHFFFAOYSA-N
애플리케이션
OBAA may be used in PLA2-mediated cell signaling studies.
생화학적/생리학적 작용
OBAA is a PLA2 inhibitor
OBAA is a phospholipase A2 inhibitor and prevents the melittin-induced influx of Ca+2 in trypanosomes.[1] It inhibits the generation of ROS when epithelial and endothelial cells are treated with cholic acid.[2]
OBAA is a potent inhibitor of phospholipases.
특징 및 장점
This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
J Eintracht et al.
The Biochemical journal, 336 ( Pt 3), 659-666 (1998-12-08)
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic
Yoshio Araki et al.
Free radical biology & medicine, 39(6), 769-780 (2005-08-20)
The barrier functions in epithelial and endothelial cells seem to be very important for maintaining normal biological homeostasis. However, it is unclear whether or how bile acids affect the epithelial barrier. We examined the bile acid-induced disruption of the epithelial
문서
Phospholipase A2 (PLA2) enzymes hydrolyze glycerophospholipids, yielding arachidonic acid; inhibition targets eicosanoid biosynthesis.
활성 필터
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