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Merck
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SMB00438

Sigma-Aldrich

Sophoricoside

≥98% (HPLC)

동의어(들):

5′,7′-Dihydroxy-4′-glucosyloxyisoflavone, Genistein-4′-O-glucoside

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크기 선택

5 MG
₩269,178
25 MG
₩797,892

₩269,178

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청
모든 사진(1)

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보기 변경
5 MG
₩269,178
25 MG
₩797,892

About This Item

실험식(Hill 표기법):
C21H20O10
CAS Number:
152-95-4
Molecular Weight:
432.38
UNSPSC 코드:
12352205
PubChem Substance ID:
329825016
NACRES:
NA.25

₩269,178

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

Quality Level

200

분석

≥98% (HPLC)

양식

powder

응용 분야

metabolomics
vitamins, nutraceuticals, and natural products

저장 온도

2-8°C

SMILES string

OC1=CC(O)=C(C(C(C2=CC=C(O[C@H]3O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]3O)C=C2)=CO4)=O)C4=C1

InChI

1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-3-1-9(2-4-11)12-8-29-14-6-10(23)5-13(24)16(14)17(12)25/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m0/s1

InChI key

ISQRJFLLIDGZEP-JDCPMNFLSA-N

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관련 카테고리

일반 설명

Sophoricoside is an isoflavone glycoside found in the fruit of Sophora japonica.[1] It is a structural isomer of genistin.[2]

생화학적/생리학적 작용

Sophoricoside (SOP) improves lipopolysaccharides (LPS)-induced acute lung injury (ALI) in mice by activating the adenosine monophosphate-activated protein kinase (AMPK)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. It also improves contact dermatitis by inhibiting the nuclear factor-kappa B (NF-κB) pathway in B cells in mice model.
Sophoricoside elicits anti-cancer, immunosuppressive, and anti-inflammatory activities.[1] It inhibits proinflammatory cytokine production in human mast cells and has the potential to treat allergic inflammation diseases.[1]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number
0000429914
0000429914
SLCQ4938
SLCQ4938
0000422977

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문서 라이브러리 방문

Su-Jin Kim et al.
Molecules (Basel, Switzerland), 18(5), 6113-6127 (2013-05-24)
Sophoricoside exhibits numerous pharmacological effects, including anti- inflammatory and anti-cancer actions, yet the exact mechanism that accounts for the anti-allergic effects of sophoricoside is not completely understood. The aim of the present study was to elucidate whether and how sophoricoside
L Chang et al.
Indian journal of pharmaceutical sciences, 75(3), 330-338 (2013-10-02)
A new, sensitive and selective high-performance liquid chromatography-tandem mass spectrometric method has been developed for the determination of six major flavonoids including sophoricoside, genistin, genistein, rutin, quercetin, kaempferol in Fructus sophorae. Principal component analysis and hierarchical clustering analysis were used
Dr. Gustavo Molina Guzmán, Chilean exile, dies at age 68.
American journal of public health, 69(2), 189-189 (1979-02-01)
Ya-Xian Wu et al.
International immunopharmacology, 90, 107187-107187 (2020-11-30)
Sophoricoside (SOP), an isoflavone glycoside isolated from seed of Sophora japonica L., has been reported to have various pharmacological activities, including anti-cancer, anti-allergy and anti-inflammation. However, the effect of SOP on lipopolysaccharides (LPS)-acute lung injury (ALI) is completely unclear. Here

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