SMB00314
Coptisine Chloride
≥98% (HPLC)
동의어(들):
Coptisine chloride, Bis(methylenedioxy)protoberberine chloride, Coptisin Chloride
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25 MG
₩584,539
About This Item
실험식(Hill 표기법):
C19H14ClNO4
CAS Number:
Molecular Weight:
355.77
MDL number:
UNSPSC 코드:
12352205
PubChem Substance ID:
NACRES:
NA.25
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
응용 분야
metabolomics
vitamins, nutraceuticals, and natural products
저장 온도
−20°C
SMILES string
C1(OCO2)=C2C=C(CC[N+]3=C4C=C5C(C(OCO6)=C6C=C5)=C3)C4=C1.[Cl-]
InChI
1S/C19H14NO4.ClH/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14;/h1-2,5-8H,3-4,9-10H2;1H/q+1;/p-1
InChI key
LUXPUVKJHVUJAV-UHFFFAOYSA-M
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일반 설명
Coptisine chloride is a cytotoxic isoquinoline alkaloid.[1] It is the major bioactive compound of Coptis rhizome[2], and can also be found in different plants such as Chelidonium majus[3], Enantia chlorantha.[1] Coptisine is related to berberine[3] and has a similar structure to that of Jatrorrhizine.[1]
애플리케이션
Coptisine Chloride has been used to study its binding interactions with single-stranded poly(A) using different absorbance and thermal melting spectroscopic experiments.[1] It may have been used as a standard to analyze Chelidonium majus L. extracted compounds using UV/VIS absorption spectroscopy.[3]
생화학적/생리학적 작용
Coptisine Chloride is a potent anti-malarial compound[2], which also exerts anti-cancer and anti-diabetic properties.[1] It elicits protective effects on gastric mucus membrane and is used as a traditional medicine against gastroenteric diseases.[1] Coptisine chloride also displays anti-microbial activities.[4]It has been analyzed as a cytotoxic agent in hepatoma and leukemic cells and is reported to block cell cycle progression.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
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이미 열람한 고객
Awet Alem Teklemichael et al.
Malaria journal, 19(1), 204-204 (2020-06-10)
Herbal medicine has been a rich source of new drugs exemplified by quinine and artemisinin. In this study, a variety of Japanese traditional herbal medicine ('Kampo') were examined for their potential anti-malarial activities. A comprehensive screening methods were designed to
Hee Seon Park et al.
Journal of veterinary science, 21(3), e39-e39 (2020-06-02)
There are various Helicobacter species colonizing the stomachs of animals. Although Helicobacter species usually cause asymptomatic infection in the hosts, clinical signs can occur due to gastritis associated with Helicobacter in animals. Among them, Helicobacter pylori is strongly associated with
Alicja Warowicka et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 64, 152919-152919 (2019-08-30)
It has been shown that secondary metabolites occur in Chelidonium majus L. (C. majus) crude extract and milky sap (alkaloids such as berberine, coptisine, chelidonine, chelerythrine, sanguinarine, and protopine) are biologically active compounds with a wide spectrum of pharmacological functions.
So Young Kim et al.
International journal of molecular sciences, 21(15) (2020-08-06)
Hepatocellular carcinoma (HCC) has a high mortality rate worldwide, and treatment is very limited due to its high recurrence and low diagnosis rate, and therefore there is an increasing need to develop more effective drugs to treat HCC. Coptisine is
Sabyasachi Chatterjee et al.
Molecular bioSystems, 13(5), 1000-1009 (2017-04-14)
All messenger RNAs (mRNAs) have a polyadenylic acid tail that is added during post transcriptional RNA processing. Investigation of the structure-function and interactions of polyadenylic acid is an important area to target for cancer and related diseases. Jatrorrhizine and coptisine
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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