추천 제품
제품명
Anti-Tubulin β antibody produced in rabbit, affinity isolated antibody
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 50 kDa
종 반응성
human, mouse, rat
농도
~1 mg/mL
기술
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TUBB3(10381)
일반 설명
Tubulin β-III (TUBB3) is a constituent of microtubules. It is expressed in mature neurons. It is located on human chromosome 16q24.
Anti-Tubulin β Antibody detects endogenous levels of total Tubulin β protein.
Anti-Tubulin β Antibody detects endogenous levels of total Tubulin β protein.
면역원
The antiserum was produced against synthesized peptide derived from human Tubulin beta.
Immunogen Range: 401-450
Immunogen Range: 401-450
애플리케이션
Anti-Tubulin β C-Terminal antibody has been used in immunoblot assays.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Immunocytochemistry (1 paper)
생화학적/생리학적 작용
Upregulation of tubulin β-III (TUBB3) shows vigorous tumor characteristics and genetic instability in urinary bladder cancer. It participates in the separation of chromosome. Individuals with congenital fibrosis of the extraocular muscle type 3 (CFEOM3) show mutations in TUBB3. βIII-tubulin modulates glucose metabolism, thereby transforms glucose starvation stress signaling to develop the multiplication of cell and survival in non-small cell lung cancer cells.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Yi-Qing Gong et al.
Oncotarget, 7(37), 60123-60132 (2016-08-16)
Excessive Ultra-violet (UV) radiation causes oxidative damages and apoptosis in retinal pigment epithelium (RPE) cells. Here we tested the potential activity of SC79, a novel small molecule activator of Akt, against the process. We showed that SC79 activated Akt in
?III-tubulin overexpression is linked to aggressive tumor features and genetic instability in urinary bladder cancer
Hinsch A, et al.
Human Pathology (2017)
Chuchu Gong et al.
Journal of cellular and molecular medicine, 27(15), 2165-2182 (2023-06-30)
Sulfur mustard (SM) is a blister-producing chemical warfare agent which could lead to a cascade of systemic damage, especially severe acute lung injury. Oxidative stress is considered to be vital processes for the SM toxicity mechanism. We previously proved the
Genome-wide gene amplification during differentiation of neural progenitor cells in vitro
Fischer U, et al.
PLoS ONE (2012)
So Youn Moon et al.
Molecular biology of the cell, 34(9), ar89-ar89 (2023-06-21)
Matrix stiffening is ubiquitous in solid tumors and can direct epithelial-mesenchymal transition (EMT) and cancer cell migration. Stiffened niche can even cause poorly invasive oral squamous cell carcinoma (OSCC) cell lines to acquire a less adherent, more migratory phenotype, but
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