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Merck
모든 사진(2)

주요 문서

S7900

Sigma-Aldrich

Saponin from quillaja bark

Sapogenin content ≥10 %

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크기 선택

25 G
₩106,677
100 G
₩186,862

₩106,677


예상 입고일2025년 1월 31일세부사항


벌크 견적 요청

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25 G
₩106,677
100 G
₩186,862

About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12161902
NACRES:
NA.32

₩106,677


예상 입고일2025년 1월 31일세부사항


벌크 견적 요청

설명

non-ionic

Quality Level

구성

Sapogenin content, ≥10%

기술

HPLC: suitable
protein quantification: suitable

황산회분

<20%

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C(=O)O)O[C@@H]3[C@@](C4[C@@](C5[C@]([C@@]6(C[C@H]([C@]7([C@H]([C@@H](C(CC7C6=CC5)(C)C)OC(=O)\C(=C/C)\C)OC(=O)C)CO)O)C)(CC4)C)(CC3)C

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일반 설명

Saponins are natural steroidal glycoside (terpenes).[1]

애플리케이션

Saponin from Quillaja bark has been used:
  • to stain CD4+ and CD8+ T-cells[2]
  • to lyse trophozoite-infected red blood cells[3]
  • in immunohistochemical staining[4]

생화학적/생리학적 작용

Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Hence it is used as vaccine adjuvants. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects.[1]
Saponins solubilize the low density lipoprotein (LDL) fraction of cholesterol in micelles, thus lowering their concentration. Saponin from Quillaja bark is used as a flavoring agent in food and beverages. This saponin has been shown to enhance immune-cell proliferation in vitro.[5][6]
Potent hemolytic when injected i.v.; surfactant that enhances penetration of proteins and other macromolecules through cell membranes; it also has been used as an adjuvant for vaccines.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Joo Young Park et al.
Journal of hazardous materials, 163(2-3), 761-767 (2008-08-12)
The applicability of microbubble suspension made of saponin as a biodegradation-enhancing carrier where oxygen and pollutant-degraders are limited was studied. The saponin-microbubble suspension was used to deliver phenanthrene-degrading bacteria, inorganic nutrients, and oxygen. Bench-scale study was carried out to determine
Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by (1)H NMR spectroscopy.
Teng R
Nmr in Biomedicine, 22(3), 292-302 (2009)
Samantha Reiss et al.
PloS one, 12(10), e0186998-e0186998 (2017-10-25)
The identification and study of antigen-specific CD4 T cells, both in peripheral blood and in tissues, is key for a broad range of immunological research, including vaccine responses and infectious diseases. Detection of these cells is hampered by both their
Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistance.
Allemand MC
PLoS ONE, 4(1), e4274-e4274 (2009)
Induction of human papillomavirus-specific CD4(+) and CD8(+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16- and 18-positive cervical cancer.
Santin AD
Journal of Virology, 73(7), 5402-5410 (1999)

질문

  1. Is this standard suitable for testing saponin content in Quillaja saponaria extracts?

    1 답변
    1. S7900 is Reagent grade of Saponin from quillaja bark. As per our policy: https://www.sigmaaldrich.com/technical-documents/technical-article/analytical-chemistry/calibration-qualification-and-validation/how-to-choose-the-correct-reference-material-quality-grade
      This product is not characterized for use as reference materials. As shown in Table 4, at least Reference Material grade is qualified for Content or Assay use. Reagent-grade products may only be suitable for identity tests.

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