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Merck
모든 사진(1)

문서

47036

Sigma-Aldrich

Saponin

for molecular biology, used as non-ionic surfactant

동의어(들):

Glycosides, Saponins

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모든 사진(1)

About This Item

CAS Number:
8047-15-2
EC Number:
232-462-6
MDL number:
MFCD00081981
UNSPSC 코드:
12161900
NACRES:
NA.25

Grade

for molecular biology

Quality Level

200

분자량

1000-2000 g/mol

구성

Sapogenin, 8-25%

기술

HPLC: suitable
protein quantification: suitable

CMC

0.001-0.01%

density

1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.)

외래 활성

DNase, RNase, Protease, Phosphatase, none detected

SMILES string

C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O

InChI

1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1

InChI key

MAEBCGDGGATMSC-OSHGGGOQSA-N

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일반 설명

Canonical SMILES: CC1(C2CCC3(C(C2(CCC1OC4C(C(C(CO4)OC5C(C(C(CO5)O)O)O)OC6C(C(C(C(O6)CO)O)O)O)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CCC91C3(CC(C2(C9CC(CC2)(C)C=O)CO1)O)C)C)C
Saponins are a large family of amphiphilic glycosides of steroids and triterpenes. Saponins are found in many plants and are localized especially in the root, tuber, bark, leaves, seed, and fruit. They are also present in some animals, like sea cucumber.

애플리케이션

Saponin has been used:
  • in phosphate-buffered saline (PBS) to block cells for immunocytochemistry and confocal microscopy
  • to permeabilize cells for measuring total mitochondrial mass
  • as an internal control to extract saponin Holothuria nobilis Selenka

Glycoside used as a nonionic sufactant and adjuvant in vaccine development.

생화학적/생리학적 작용

Saponins are nonionic surfactant that forms oil-in-water emulsions and acts as a protective colloid. They are used for the direct determination of metals in milk by flame atomic absorption spectrophotometry.
Saponins exhibit anti-tumor, antimicrobial, and anti-herbivore activity. They may also play a key role in plant defense. Saponins also possess several pharmaceutical properties, like anti-inflammatory, antifungal, antibacterial, anti-parasitic, and antiviral activities. Saponins can regulate rhizosphere bacteria in the soil.

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

시험 성적서(COA)

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