Q2128
Quisqualic acid
powder
동의어(들):
β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
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모든 사진(1)
크기 선택
보기 변경
1 MG
₩184,832
5 MG
₩629,097
10 MG
₩947,097
25 MG
₩2,107,749
About This Item
실험식(Hill 표기법):
C5H7N3O5
CAS Number:
Molecular Weight:
189.13
Beilstein:
1078734
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.32
추천 제품
양식
powder
색상
white to off-white
solubility
ethanol: <0.17 mg/mL
H2O: 0.5 mg/mL
0.1 M HCl: 1.4 mg/mL
1 M NH4OH: 20 mg/mL
organic solvents: insoluble
저장 온도
2-8°C
SMILES string
N[C@@H](CN1OC(=O)NC1=O)C(O)=O
InChI
1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
InChI key
ASNFTDCKZKHJSW-REOHCLBHSA-N
유전자 정보
rat ... Gria1(50592) , Grik1(29559) , Grin2a(24409) , Grm1(24414) , Grm2(24415) , Grm4(24417) , Grm5(24418)
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일반 설명
Quisqualate/ Quisqualic acid is obtained from the fruits and seeds of Quisqualis chinensis. It is an agonist at two subsets of excitatory amino acid receptors metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores and, ionotropic receptors that directly control membrane channels. L-quisqualic acid is an agonist of the neurotransmitter L-glutamate.[1][2]
애플리케이션
Quisqualic acid has also been used as a group I metabotropic receptor agonist in neurons.[3]
Quisqualic acid has been used to test ligand-gated receptors in spiral ganglion neurons.[4]
생화학적/생리학적 작용
Active enantiomer of quisqualic acid; excitatory amino acid at glutamate receptors.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
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시험 성적서(COA)
Lot/Batch Number
Optical recordings of Ca2+ signaling activities from identified inner ear cells in cochlear slices and hemicochleae
Xi Lin
Brain Res. Protoc., 11(2) (2003)
Sujeenthar Tharmalingam et al.
Neuropharmacology, 63(4), 667-674 (2012-06-02)
The metabotropic glutamate receptors (mGluRs) are evolutionarily conserved from nematodes to vertebrates. The Caenorhabditis elegans (C. elegans) genome contains three mGluR genes referred to as mgl-1, mgl-2, and mgl-3. The aim of this study was to characterize the pharmacological profiles
Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload
Plotegher N, et al.
Cell Death and Differentiation, 27(5), 1588-1603 (2020)
Chinese Drugs of Plant Origin: Chemistry, Pharmacology, and Use in Traditional and Modern Medicine null
Pablo J Giraudi et al.
PloS one, 6(12), e29078-e29078 (2012-01-05)
We have previously reported that exposure of SH-SY5Y neuroblastoma cells to unconjugated bilirubin (UCB) resulted in a marked up-regulation of the mRNA encoding for the Na(+)-independent cystine∶glutamate exchanger System X(c)(-) (SLC7A11 and SLC3A2 genes). In this study we demonstrate that
활성 필터
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