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주요 문서

P0883

Sigma-Aldrich

Poly(deoxyadenylic-thymidylic) acid sodium salt

double-stranded alternating copolymer

동의어(들):

Poly(dA-dT) • Poly(dA-dT)

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크기 선택

10 UNITS
₩575,708
25 UNITS
₩1,003,226
50 UNITS
₩1,722,354

₩575,708


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

크기 선택

보기 변경
10 UNITS
₩575,708
25 UNITS
₩1,003,226
50 UNITS
₩1,722,354

About This Item

CAS Number:
MDL number:
UNSPSC 코드:
41106305
NACRES:
NA.51

₩575,708


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

양식

powder

저장 온도

−20°C

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애플리케이션

Poly(deoxyadenylic-thymidylic) (Poly(dA-dT) • Poly(dA-dT))acid is a double-stranded alternating copolymer DNA model for conformational studies of DNA structure dynamics and drug interaction.

기타 정보

Double-stranded alternating copolymer.

단위 정의

One unit will yield an A260 of 1.0 in 1.0 ml 20 mM sodium phosphate/100 mM NaCl, pH 7.0 (1cm light path).

수량

One mg is equivalent to ≥12 A260 units.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Marta Airoldi et al.
Journal of biomolecular structure & dynamics, 25(1), 77-84 (2007-08-07)
The thermal denaturation of the synthetic high molecular weight double stranded polynucleotide poly(dA-dT) x poly(dA-dT) has been studied in aqueous buffered solution (Tris 1.0 mM; pH 7.8+/-0.2) in the presence of increasing concentrations of either Ni(2+) (borderline cation) or Cd(2+)
M Vorlícková et al.
Journal of biomolecular structure & dynamics, 3(1), 67-83 (1985-08-01)
The article reviews data indicating that poly(dA-dT).poly(dA-dT) is able of adopting three distinct double helical structures in solution, of which only the A form conforms to classical notions. The other two structures have dinucleotides as double helical repeats. At low
Marta Airoldi et al.
Chirality, 20(9), 951-960 (2008-02-05)
The thermal behavior of the synthetic, high molecular weight, double stranded polynucleotides poly(dA-dT).poly(dA-dT) [polyAT] and poly(dG-dC).poly(dG-dC) [polyGC] solubilized in the aqueous core of the quaternary water-in-oil cationic microemulsion CTAB|n-pentanol|n-hexane|water in the presence of increasing amounts of NiCl(2) at several constant
Creina Slator et al.
ACS chemical biology, 11(1), 159-171 (2015-10-22)
The in cellulo catalytic production of reactive oxygen species (ROS) by copper(II) and iron(II) complexes is now recognized as a major mechanistic model in the design of effective cytotoxins of human cancer. The developmental complex, [Cu(o-phthalate)(1,10-phenanthroline)] (Cu-Ph), was recently reported
Natasha McStay et al.
Nucleic acids research, 45(2), 527-540 (2016-12-03)
Herein we report the synthesis of tripodal C

질문

1–4 / 4 질문  
  1. What is the difference between Poly(deoxyadenylic-thymidylic) acid sodium salt Products P0883 and P5782?

    1 답변
    1. Prod. No. P0883 is from a different supplier than Prod. No. P5782.  Chain lengths for both products can vary from batch to batch.  According to information from our suppliers, the A250/A260 ratios are similar, but the A280/A260 ratio for Prod. No. P0883 will be slightly higher than that of Prod. No. P5782.

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  2. What is the Department of Transportation shipping information for this product?

    1 답변
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  3. What is the sequence of Product P0883, Poly(deoxyadenylic-thymidylic) acid sodium salt?

    1 답변
    1. This product is a double-stranded alternating DNA copolymer, although it is possible for single strands to be present.  The sequence of each strand is an alternating sequence of dAdTdAdTdAdT….. or dATdATdATdAT… since dT (deoxythymidylic acid) and T (thymidylic acid) are the same.

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  4. In what should Product P0883, Poly(deoxyadenylic-thymidylic) acid sodium salt, be dissolved?

    1 답변
    1. Per our supplier, to maintain a double stranded configuration of the polymer in solution, it should be rehydrated with a neutral buffer containing 100 mM NaCl.  After reconstitution, the polymer solution should be stored at -20°C.

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