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Merck
모든 사진(3)

주요 문서

O2136

Sigma-Aldrich

Oleamide

≥99% (TLC), powder, sleep-inducing brain lipid

동의어(들):

cis-9,10-Octadecenoamide, cis-9-Octadecenamide, Oleic acid amide

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100 MG
₩282,678
500 MG
₩720,853

₩282,678


예상 입고일2025년 4월 07일세부사항


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보기 변경
100 MG
₩282,678
500 MG
₩720,853

About This Item

실험식(Hill 표기법):
C18H35NO
CAS Number:
Molecular Weight:
281.48
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

₩282,678


예상 입고일2025년 4월 07일세부사항


벌크 견적 요청

제품명

Oleamide, ≥99%

분석

≥99%

약물 제어

regulated under CDSA - not available from Sigma-Aldrich Canada

저장 온도

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(N)=O

InChI

1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-

InChI key

FATBGEAMYMYZAF-KTKRTIGZSA-N

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일반 설명

Oleamide is a lipid[1] or a brain fatty acid, that is found in the CSF (cerebrospinal fluid).[2] It is originally obtained from the cerebrospinal fluid of cats, that are sleep-deprived.[3]

애플리케이션

Oleamide has been used as a supplement in glucose and galactose media to prevent the rescue of galactose-induced Leigh syndrome (LS).[4]

생화학적/생리학적 작용

Oleamide has the ability to stimulate sleep.[2] It possess several properties, like cannabinoid-like activity.[1] Oleamide can also disable the communication, facilitated by gap junction between rat glial cells.[3]
Sleep-inducing brain lipid, which allosterically modulates GABAA receptors and potentiates 5-HT7 serotonin receptor responses. Selective endogenous agonist of rat and human CB1 cannabinoid receptor.

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

404.6 °F - closed cup

Flash Point (°C)

207 °C - closed cup

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Mónica Méndez-Díaz et al.
Addiction biology, 17(4), 725-735 (2010-12-25)
Endocannabinoids (eCBs) are mediators of the homeostatic and hedonic systems that modulate food ingestion. Hence, eCBs, by regulating the hedonic system, may be modulating the valence of the emotion associated to food ingestion (positive: pleasant or negative: unpleasant). Our first
Lidong Zhang et al.
Langmuir : the ACS journal of surfaces and colloids, 29(1), 65-74 (2012-12-12)
A series of oleamide derivatives, (C(18)H(34)NO)(2)(CH(2))(n) [n = 2 (1a), 3 (1b), 4 (1c), or 6 (1d); C(18)H(34)NO = oleic amide fragment] and (C(18)H(34)NO)(CH(2))(6)NH(2) (2), have been synthesized and their self-assembly is investigated in ethanol/water media. Self-assembly of 1a and
Oleamide and anandamide effects on food intake and sexual behavior of rats
Martinez-Gonzalez D, et al.
Neuroscience Letters, 364(1), 1-6 (2004)
The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells
Guan X, et al.
The Journal of Cell Biology, 139(7), 1785-1792 (1997)
Varadarajan Sudhahar et al.
European journal of pharmacology, 607(1-3), 143-150 (2009-03-28)
Fatty acid amides are a new class of signaling lipids that have been implicated in diverse physiological and pathological conditions. Oleamide is a fatty acid amide that induces vasorelaxation. Here, we investigated the mechanisms behind the vasorelaxation effect of oleamide

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지질 신호전달 연구를 위한 생체 활성 저분자

Discover Bioactive Small Molecules for Lipid Signaling Research

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