O1383

Oleic acid

BioReagent, suitable for cell culture

• 동의어(들): cis-9-Octadecenoic acid, Elainic acid
• Linear Formula: CH₃(CH₂)₇CH=CH(CH₂)₇COOH
• CAS Number: 112-80-1
• Molecular Weight: 282.46
• Beilstein: 1726542
• EC Number: 204-007-1
• MDL number: MFCD00064242
• UNSPSC 코드: 12352211
• PubChem Substance ID: 24897941
• NACRES: NA.75

속성

• 생물학적 소스: palm oil
• vapor pressure: 1 mmHg ( 176 °C)
• 제품 라인: BioReagent
• 분석: ≥99% (GC)
• 형태: viscous liquid
• 기술: cell culture | mammalian: suitable
• refractive index: n20/D 1.459 (lit.)
• bp: 194-195 °C/1.2 mmHg (lit.)
• mp: 13-14 °C (lit.)
• solubility: ethanol: soluble
• density: 0.89 g/mL at 25 °C (lit.); 0.89 g/mL at 25 °C (lit.)
• 저장 온도: −20°C
• SMILES string: CCCCCCCC\C=C/CCCCCCCC(O)=O
• InChI: 1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
• InChI key: ZQPPMHVWECSIRJ-KTKRTIGZSA-N
• 유전자 정보: human ... SOAT1(6646) , SOAT2(8435)

설명

일반 설명

Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is not an essential fatty acid (EFA); however, providing it to cells in culture reduces energy demand.

Oleic acid mediates complete oxidation of fatty acid in sirtuin1- proliferator-activated receptor γ coactivator−1α (SIRT1-PGC-1α) signalling pathway. Oleic acid shows anti-inflammatory properties related to atherosclerosis and insulin resistant state. Oleic acid inhibits permeability in gap junctions and promotes glucose uptake in astrocytes. Oleic acid aids in neural cell proliferation by increasing glucose uptake and by protein kinase C (PKC) activation. Oleic acid is essential for axonal growth and neuronal clustering.

애플리케이션

Oleic acid has been used:

• in fatty acid oxidation rate experiments in myotubes and in Sirt1 enzyme assay
• to determine quantitatively its effect on lipid droplets by optical diffraction tomography
• as a fatty acid source in the medium for primary hepatocyte culture

포장

Sealed ampule.

주의사항

Unsaturated fatty acids are subject to oxidation and peroxidation. Consider complexed fatty acid supplements.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter