모든 사진(1)
About This Item
실험식(Hill 표기법):
C9H8N2O2
CAS Number:
Molecular Weight:
176.17
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
≥97% (HPLC)
형태
solid
색상
off-white
solubility
DMSO: soluble >20 mg/mL
H2O: insoluble
저장 온도
−20°C
SMILES string
CC1=Nc2c(O)cccc2C(=O)N1
InChI
1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13)
InChI key
YJDAOHJWLUNFLX-UHFFFAOYSA-N
유전자 정보
mouse ... Parp2(11546)
생화학적/생리학적 작용
NU-1025 is a PARP inhibitor.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Quanju Zhao et al.
Journal of immunology (Baltimore, Md. : 1950), 198(7), 2935-2942 (2017-02-22)
IL-12 and IL-23 are important host defense factors produced by APCs against certain intracellular and extracellular pathogens. Their dysregulation has also been implicated in several autoimmune diseases. The nucleotide polymorphism in the promoter region of Il12b (rs41292470 consisting of the
David Zada et al.
Molecular cell, 81(24), 4979-4993 (2021-11-20)
The characteristics of the sleep drivers and the mechanisms through which sleep relieves the cellular homeostatic pressure are unclear. In flies, zebrafish, mice, and humans, DNA damage levels increase during wakefulness and decrease during sleep. Here, we show that 6 h
Evangelos Koustas et al.
Journal of cellular and molecular medicine, 24(18), 10420-10431 (2020-07-21)
Gastric cancer is the fifth most common malignancy and the third leading cause of cancer-related death worldwide. Activation of c-MET increases tumour cell survival through the initiation of the DNA damage repair pathway. PARP is an essential key in the
Michael M Murata et al.
Molecular biology of the cell, 30(20), 2584-2597 (2019-08-08)
DNA damage signaling is critical for the maintenance of genome integrity and cell fate decision. Poly(ADP-ribose) polymerase 1 (PARP1) is a DNA damage sensor rapidly activated in a damage dose- and complexity-dependent manner playing a critical role in the initial
Yang Sun et al.
American journal of respiratory cell and molecular biology, 51(6), 738-749 (2014-05-31)
Lymphangioleiomyomatosis (LAM) is a female-predominant cystic lung disease that can lead to respiratory failure. LAM cells typically have inactivating tuberous sclerosis complex 2 (TSC2) mutations and mammalian target of rapamycin (mTOR) complex (mTORC) 1 activation. Clinical response to the mTORC1
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