N4913

Anti-NOTCH2 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-Notch homolog 2 (Drosophila)
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen ~230 kDa (extracellular); antigen ~280 kDa
• 종 반응성: human
• 농도: ~1 mg/mL
• 기술: western blot: 1:500-1:1,000
• UniProt 수납 번호: Q04721
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... NOTCH2(4853) ; mouse ... Notch2(18129) ; rat ... Notch2(29492)

설명

일반 설명

NOTCH homolog-2 (NOTCH2) is part of the NOTCH signaling pathway and the gene encoding it is localized on chromosome 1p13-p11.

면역원

synthetic peptide corresponding to residues 1718-1733 of human NOTCH2. This sequence is 93% identical in mouse and rat.

생화학적/생리학적 작용

NOTCH homolog-2 (NOTCH2) is a stimulator of metaplasia in goblet cells, which is seen in respiratory diseases like asthma. Mutations in the NOTCH2 gene are associated with Hajdu-Cheney syndrome.

물리적 형태

solution in phosphate buffered saline, containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)