This product meets 4X the minimum USP specifications. According to the USP monograph for Pancreatin, the 1X minimum specification is 25 USP units amylase, 2 USP units lipase, and 25 USP units protease per milligram. The calculated protease activity for the 4X preparation then, would be at least 100 units per milligram. This is a calculated value based on the USP monograph and are not reported separately on the Certificate of Analysis.
추천 제품
Agency
USP (specifications)
양식
powder
특이 활성도
4 × USP specifications
포함
lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)
저장 온도
−20°C
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관련 카테고리
애플리케이션
Pancreatin from porcine pancreas has been used:
- for a study to assess the treatment of steatorrhea by lipase supplementation therapy[1]
- for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis[2]
- to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity [3]
- to assess cleavage by digestive enzymes.
- for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors.[4]
- along with amyloglucosidase for the in vitro digestion of starch in food samples.[5]
생화학적/생리학적 작용
Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Peter Layer et al.
Pancreas, 26(1), 1-7 (2002-12-25)
Treatment of steatorrhea by lipase supplementation therapy has become more successful in the last decade due to better understanding of the physiology and pathophysiology of the digestive process. Porcine lipase has been the therapeutic standard for several decades and will
David C Whitcomb et al.
Digestive diseases and sciences, 52(1), 1-17 (2007-01-06)
A primary function of the pancreas is to produce digestive enzymes that are delivered to the small intestine for the hydrolysis of complex nutrients. Much of our understanding of digestive enzymes comes from studies in animals. New technologies and the
Asavela Ngalavu et al.
Animals : an open access journal from MDPI, 10(4) (2020-04-17)
Feed fiber composition is usually considered as one of the factors that have an impact on digestive tract microbiota composition. The investigations on the level of fermentation and in-vitro digestibility of different fibers are not well understood. The aim of
Muhammad Awais et al.
Foods (Basel, Switzerland), 9(5) (2020-05-28)
The changes in structure and digestion properties of mung bean starch due to hydrothermal treatment at various controlled temperatures were investigated. Results showed the increase in onset temperature (To) from 66.33 °C to 76.69 °C and decrease in enthalpies (∆Hg
Gabriele Rocchetti et al.
Antioxidants (Basel, Switzerland), 9(4) (2020-04-10)
In this work, different commercial extra-virgin olive oils (EVOO) were subjected to in vitro gastrointestinal digestion and the changes in bioactive compounds were evaluated by ultra-high-pressure liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry, using untargeted metabolomics. As expected, raw EVOO
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units of pancreatin cas number 8049-47-6
1 답변-
도움이 되었습니까?
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What is the trypsin activity of this P1750 product ?
1 답변-
This product is not specifically tested for trypsin activity. The material meets USP requirements. This monograph includes testing for protease, amylase, and lipase.
도움이 되었습니까?
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What is the solubility of p1750 pancreatin in water?
1 답변-
This product is soluble at 7 mg/mL in water and may yield a hazy solution.
도움이 되었습니까?
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As per USP: Pancreatin contains, in each mg, not less than 25 USP Units of protease activity. I assume that product P1750 contains minimum 100 USP units of protease activity in each mg. What is the maximum USP units of protease activity in P1750 ?
1 답변-
Yes, this is correct. To meet the USP specifications, the protease activity will be less than 100 USP Units/mg.
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활성 필터
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