L0649
Leupeptin hydrochloride
powder, ≥70% (HPLC)
동의어(들):
Acetyl-Leu-Leu-Arg-al hydrochloride
로그인조직 및 계약 가격 보기
크기 선택
5 MG
₩154,382
25 MG
₩541,198
100 MG
₩1,656,785
₩154,382
출고 가능일2025년 4월 07일세부사항
모든 사진(1)
크기 선택
보기 변경
5 MG
₩154,382
25 MG
₩541,198
100 MG
₩1,656,785
About This Item
실험식(Hill 표기법):
C20H38N6O4 · HCl
CAS Number:
Molecular Weight:
463.01
MDL number:
UNSPSC 코드:
12352202
PubChem Substance ID:
NACRES:
NA.77
₩154,382
출고 가능일2025년 4월 07일세부사항
추천 제품
제품명
Leupeptin hydrochloride, microbial, ≥70% (HPLC)
생물학적 소스
microbial
Quality Level
분석
≥70% (HPLC)
양식
powder
solubility
water: 50 mg/mL, clear, colorless to yellow
저장 온도
−20°C
SMILES string
Cl.CC(C)CC(NC(C)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(N)=N)C=O
InChI
1S/C20H38N6O4.ClH/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);1H
InChI key
OQQYPQNFLLAILR-UHFFFAOYSA-N
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생화학적/생리학적 작용
Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM.
Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)
분석 메모
Leupeptin gives multiple peaks on HPLC because of the formation of tautomeric isomers in solution. Majority of contaminating peptide is racemized leupeptin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
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활성 필터
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