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Merck
모든 사진(1)

주요 문서

I2516

Sigma-Aldrich

Isocitric Dehydrogenase (NADP) from porcine heart

lyophilized powder, 20-60 units/mg protein (biuret)

동의어(들):

threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH, IDH

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About This Item

CAS Number:
효소 위원회 번호:
EC Number:
MDL number:
UNSPSC 코드:
12352204

양식

lyophilized powder

특이 활성도

20-60 units/mg protein (biuret)

구성

Protein, ~20%

저장 온도

−20°C

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품질

Highly purified
Essentially free of aconitase activity.

단위 정의

One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C.

물리적 형태

Lyophilized powder containing sodium citrate and manganous sulfate

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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문서 라이브러리 방문

O Zalatimo et al.
Advances in experimental medicine and biology, 779, 267-289 (2013-01-05)
Primary brain tumors constitute a substantial public health problem with 66,290 cases diagnosed in the US in 2012, and 13,700 deaths recorded. With discovery of genetic factors associated with specific brain tumor subtypes, the goal of therapy is changing from
Lynn J Poole Perry et al.
American journal of ophthalmology, 155(3), 593-608 (2012-12-12)
To evaluate the cellular nature of and diagnostic terminology used in connection with acquired retinal "vasoproliferative tumors." Retrospective clinicopathologic study. Clinical records and microscopic slides of 4 enucleated globes were reviewed. Special stains and immunohistochemical probes for CD31, CD34, p53
Juan C Begara-Morales et al.
Journal of experimental botany, 64(4), 1121-1134 (2013-01-31)
Protein tyrosine nitration is a post-translational modification mediated by reactive nitrogen species (RNS) that is associated with nitro-oxidative damage. No information about this process is available in relation to higher plants during development and senescence. Using pea plants at different
Frank G Schaap et al.
Advances in anatomic pathology, 20(1), 32-38 (2012-12-13)
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observed in specific types of cartilaginous tumors, gliomas, and leukemias. Mutant IDH enzyme loses its normal activity to convert isocitrate into α-ketoglutarate (αKG) and instead acquires the ability
Varuna Sipayya et al.
Journal of cancer research and therapeutics, 8(4), 598-601 (2013-01-31)
Mutations in the gene encoding isocitrate dehydrogenase (IDH1) have been reported in gliomas. This study analyses a series of 184 glioma cases in a tissue microarray (TMA)-based approach to assess the frequency of R132H point mutations in formalin-fixed, paraffin-embedded tissue

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