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H9039

Sigma-Aldrich

Hemin

from bovine, ≥90%

동의어(들):

Chloro(protoporphyrinato)iron(III), Chlorohemin, Chloroprotoporphyrin IX iron(III), Ferriprotoporphyrin IX chloride, Hemin(chloride)

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크기 선택

1 G
₩113,680
10 G
₩771,096
100 G
₩1,498,445

₩113,680

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청
모든 사진(3)

크기 선택

보기 변경
1 G
₩113,680
10 G
₩771,096
100 G
₩1,498,445

About This Item

실험식(Hill 표기법):
C34H32ClFeN4O4
CAS Number:
16009-13-5
Molecular Weight:
651.94
Beilstein:
5229914
EC Number:
240-140-1
MDL number:
MFCD00010726
UNSPSC 코드:
12352202
PubChem Substance ID:
329815257
NACRES:
NA.61

₩113,680

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

생물학적 소스

bovine

분석

≥90%

양식

powder

기술

toxicology assay: suitable

solubility

1.4 M NH4OH: soluble 25 mg/mL

저장 온도

2-8°C

SMILES string

Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Fe](Cl)n34)c(C=C)c5C

InChI

1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChI key

BTIJJDXEELBZFS-HXFTUNQESA-K

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Heme is a small molecule present either free or bound to hemoglobin in the bloodstream of mammals. This is an alternative source of iron within the host that contains a porphyrin ring containing a Fe2+ ion called hemin. [1]

애플리케이션

Hemin was used to study conjugation, characterization and toxicity of lipophosphoglycan-polyacrylic acid conjugate for vaccination against leishmaniasis.[2]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
0000411611
0000411611
0000400593
0000400594
0000398969

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문서 라이브러리 방문

이미 열람한 고객

Slide 1 of 1

1 of 1

Protoporphyrin IX disodium salt ≥90% (HPLC)

Sigma-Aldrich

258385

Protoporphyrin IX disodium salt

Murat Topuzogullari et al.
Journal of biomedical science, 20, 35-35 (2013-06-05)
Research on the conjugates of synthetic polyelectrolytes with antigenic molecules, such as proteins, peptides, or carbohydrates, is an attractive area due to their highly immunogenic character in comparison to classical adjuvants. For example, polyacrylic acid (PAA) is a weak polyelectrolyte
Post-embryonic development in Caenorhabditis elegans.
D L Riddle
International journal for parasitology, 17(1), 223-231 (1987-02-01)
Xiaoyu Shi et al.
Molecular microbiology, 114(3), 454-467 (2020-05-21)
Reticulon and REEP family of proteins stabilize the high curvature of endoplasmic reticulum (ER) tubules. Plasmodium berghei Yop1 (PbYop1) is a REEP5 homolog in Plasmodium. Here, we characterize its function using a gene-knockout (Pbyop1∆). Pbyop1∆ asexual stage parasites display abnormal
Rodgoun Attarian et al.
mBio, 9(6) (2018-12-06)
The acquisition of iron and the maintenance of iron homeostasis are important aspects of virulence for the pathogenic fungus Cryptococcus neoformans In this study, we characterized the role of the monothiol glutaredoxin Grx4 in iron homeostasis and virulence in C.
Alberto J Ruiz et al.
Journal of biomedical optics, 25(5), 1-15 (2020-05-23)
Expanded use of fluorescence-guided surgery with devices approved for use with indocyanine green (ICG) has led to a range of commercial systems available. There is a compelling need to be able to independently characterize system performance and allow for cross-system
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질문

1–8 / 8 질문  

  1. Recently got 1G of the product - H9039. Do I have to dissolve in a solution?

    1 답변

    1. This product is supplied in powder form and needs to be reconstituted. It is soluble in 1.4 M ammonium hydroxide at 25 mg/mL. Please review the product data page at: https://www.sigmaaldrich.com/product/sigma/h9039

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  2. What is the solvent medium, to dissolve hemin stock powder and what is stock concentration of hemin (H9039)

    1 답변

    1. This product is tested for solubility at 25 mg/mL in 1.4 M NH4OH. According to a published article, this material is also soluble at 50 mg/mL in 1.0 M NaOH. Please see the link below to review this publication:
      https://journals.asm.org/doi/10.1128/iai.01924-05

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  3. What is the recommended method of sterilization in a culture medium with Hemin addition? Autoclaving at 112°C or filter sterilization?

    1 답변

    1. Stock solutions of Hemin are typically added to medium and autoclaved at 121 °C for 15-20 minutes. Stock solutions may also be filter sterilized and added aseptically to sterile medium.

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  4. I couln´t understand when you say: "There is no shelf life date assigned to this product. The guarantee of quality is for one year from the time of shipment for bottles stored as recommended." Then for Hemin - from bovine we will not have a Exp.date?

    1 답변

    1. A number of products are not included in expiration testing programs, as there is no indication to conclude they are unstable. The only date shown on the certificate of analysis will be the Release Date. For these products there is no stated Retest, Expiration or Use-by-Date Date. We recommend handling per defined conditions as printed in our product literature and website product descriptions. Products should be routinely inspected by the customer to ensure they perform as expected. For those products, only our standard warranty of 1 year from the date of shipment of products is applicable. For further information on our warranty please refer to terms and conditions of sale.

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  5. What are some applications for Hemin, Product H9039?

    1 답변

    1. Hemin-agarose has reportedly been prepared for use in affinity chromatography of heme-binding proteins.  See Tsutsui, K., Affinity chromatography of heme-binding proteins: Synthesis of hemin-agarose. Meth. Enzymol. 123, 331, (1986). Sigma supplies a hemin agarose, product H6390. Hemin can also be used as a component in culture media for the cultivation of bacteria, such as Leishmania tarentolae.

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  6. What is the shelf life for Hemin, Product H9039?

    1 답변

    1. There is no shelf life date assigned to this product. The guarantee of quality is for one year from the time of shipment for bottles stored as recommended.

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  7. What is the Department of Transportation shipping information for this product?

    1 답변

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  8. How stable is Hemin, Product H9039, in solution?

    1 답변

    1. Sigma-Aldrich has not evaluated the solution stability of hemin solutions.  Also, we have not found any information on solution storage in the literature. We recommend that solutions be prepared fresh.

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