콘텐츠로 건너뛰기
Merck
모든 사진(1)

주요 문서

H0536

Sigma-Aldrich

Hepatocyte Growth Factor Receptor (c-Met)/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

동의어(들):

HGF Receptor (c-Met)

로그인조직 및 계약 가격 보기


About This Item

MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.32
가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.

생물학적 소스

human

Quality Level

재조합

expressed in NSO cells

분석

>95% (SDS-PAGE)

양식

lyophilized powder

효능

0.1-5 ng/mL

분자량

calculated mol wt 129 kDa

포장

pkg of 100 μg

저장 조건

avoid repeated freeze/thaw cycles

불순물

endotoxin, tested

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

human ... MET(4233)

생화학적/생리학적 작용

Heterodimeric transmembrane glycoprotein with binding capacity for c-Met. Activation of this receptor has been correlated with induction of the Ras pathway.

기타 정보

Extracellular domain of c-Met fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.

물리적 형태

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing 5 mg bovine serum albumin.

분석 메모

The biological activity is measured by its ability to bind human HGF.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Yaroslava M Chalenko et al.
International journal of molecular sciences, 24(8) (2023-04-28)
Listeria monocytogenes virulence factor InlB specifically interacts with the receptors c-Met and gC1q-R. Both receptors are present in non-professional and professional phagocytes, including macrophages. Phylogenetically defined InlB isoforms differently support invasion into non-professional phagocytes. This work deals with the effects
M Park et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(18), 6379-6383 (1987-09-01)
We isolated overlapping cDNA clones corresponding to the major MET protooncogene transcript. The cDNA nucleotide sequence contained an open reading frame of 1408 amino acids with features characteristic of the tyrosine kinase family of growth factor receptors. These features include
Egor V Kalinin et al.
Drug development research, 82(1), 123-132 (2020-08-25)
Hepatocyte growth factor (HGF) is central to liver regeneration. The Internalin B (InlB) protein is a virulence factor produced by the pathogenic bacterium Listeria monocytogenes. InlB is known to mimic HGF activity by interacting with the HGF receptor (HGFR) and
Xin Li et al.
Frontiers in cell and developmental biology, 9, 661122-661122 (2021-05-04)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with minimally effective treatments, highlighting the importance of developing novel biomarkers and therapeutic targets. Here, we disclosed the mechanisms that leukocyte cell-derived chemotaxin-2 (LECT2) modulates PDAC development using in

질문

후기

평점 값 없음

활성 필터

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.