F5178

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

• 동의어(들): FMO-5
• 효소 위원회 번호: 1.14.13.8 (BRENDA, IUBMB)
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 재조합: expressed in baculovirus infected insect cells
• Quality Level: 200
• 양식: buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
• 특이 활성도: ≥700 units/mg protein
• 분자량: 55-60 kDa
• 포장: vial of 2.5 mg
• UniProt 수납 번호: P49326
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... FMO5(2330)

설명

애플리케이션

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

생화학적/생리학적 작용

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

단위 정의

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

물리적 형태

Solution in 100 mM potassium phosphate buffer, pH 7.4.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)