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Merck
모든 사진(1)

문서

D7692

Sigma-Aldrich

Diethylumbelliferyl phosphate

≥98% (HPLC), oil

동의어(들):

DEUP, UBP

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C14H17O6P
CAS Number:
Molecular Weight:
312.25
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

형태

oil

색상

colorless to yellow

solubility

DMSO: >5 mg/mL

저장 온도

−20°C

SMILES string

CCOP(=O)(OCC)Oc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C14H17O6P/c1-4-17-21(16,18-5-2)20-11-6-7-12-10(3)8-14(15)19-13(12)9-11/h6-9H,4-5H2,1-3H3

InChI key

GHGRYKAFUNNHBG-UHFFFAOYSA-N

관련 카테고리

애플리케이션

Diethylumbelliferyl phosphate has been used as a lipase inhibitor to treat wild-type myeloblasts for in vitro neutrophil differentiation assays.

생화학적/생리학적 작용

Diethylumbelliferyl phosphate (DEUP), an organophosphate does not block protein kinase activity A in vitro.
Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC50 = 11.6 μM.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


시험 성적서(COA)

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문서 라이브러리 방문

Momoko Yamagata et al.
Experimental brain research, 236(5), 1501-1517 (2018-03-23)
We explored the relations between indices of mechanical stability of vertical posture and synergy indices under unexpected perturbations. The main hypotheses predicted higher posture-stabilizing synergy indices and higher mechanical indices of center of pressure stability during perturbations perceived by subjects
J G Delamatre et al.
Journal of cellular physiology, 157(1), 164-168 (1993-10-01)
Diethylumbelliferyl phosphate (UBP) has been shown to inhibit the neutral cholesteryl ester hydrolase activity responsible for hydrolysis of cellular lipid droplet cholesteryl ester (Harrison et al., 1990). The potential for (UBP) to inhibit uptake and hydrolysis of high density lipoprotein
P M Gocze et al.
Cytometry, 17(2), 151-158 (1994-10-01)
Neutral lipids accumulate in cellular lipid droplets. These droplets vary remarkably in number and amount between cells. In the present studies, the variability in lipid content was quantified by comparing the coefficient of variation of fluorescence histograms of nile red
Stephen A Brose et al.
Rapid communications in mass spectrometry : RCM, 26(20), 2472-2476 (2012-09-15)
Fatty acids (FA) labeled with (18) O at the carboxyl group, including oxidized species (FA(18) O), are a useful, low-cost, and easy to prepare tool for quantitative and qualitative mass spectrometry (MS) analysis in biological systems. In addition, they are
Daniel P Heil et al.
Journal of the International Society of Sports Nutrition, 9, 8-8 (2012-03-22)
Previous research has shown that ingestion of substances that enhance the body's hydrogen ion buffering capacity during high intensity exercise can improve exercise performance. The present study aimed to determine whether the chronic ingestion of an alkalizing supplement, which purports

문서

Cholesterol esterification enhances transport efficiency in lipoproteins for increased blood stream transport.

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