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주요 문서

D1878

Sigma-Aldrich

2,6-Dichloroindophenol sodium salt hydrate

Powder, BioReagent

동의어(들):

2,6-Dichloro-N-(4-hydroxyphenyl)-1,4-benzoquinoneimine sodium salt, 2,6-Dichlorobenzenone-indophenol sodium salt, 2,6-Dichlorophenolindophenol sodium salt hydrate, DCIP, DPIP

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크기 선택

5 G
₩145,653
25 G
₩378,088

₩145,653


예상 입고일2025년 1월 31일세부사항


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크기 선택

보기 변경
5 G
₩145,653
25 G
₩378,088

About This Item

실험식(Hill 표기법):
C12H6Cl2NNaO2 · xH2O
CAS Number:
Molecular Weight:
290.08 (anhydrous basis)
Beilstein:
3641229
EC Number:
MDL number:
UNSPSC 코드:
12171500
PubChem Substance ID:
NACRES:
NA.47

₩145,653


예상 입고일2025년 1월 31일세부사항


벌크 견적 요청

제품명

2,6-Dichloroindophenol sodium salt hydrate, suitable for vitamin C determination, BioReagent

제품 라인

BioReagent

Quality Level

양식

powder

solubility

H2O: soluble 10 mg/mL, clear, blue to very deep blue

적합성

suitable for vitamin C determination

응용 분야

diagnostic assay manufacturing
food and beverages
hematology
histology

저장 온도

room temp

SMILES string

O.[Na+].[O-]c1ccc(cc1)\N=C2/C=C(Cl)C(=O)C(Cl)=C2

InChI

1S/C12H7Cl2NO2.Na.H2O/c13-10-5-8(6-11(14)12(10)17)15-7-1-3-9(16)4-2-7;;/h1-6,16H;;1H2/q;+1;/p-1

InChI key

XHSOLXWCGCVQHE-UHFFFAOYSA-M

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

2,6-Dichloroindophenol sodium salt hydrate is a blue redox dye.

애플리케이션

2,6-Dichloroindophenol sodium salt hydrate is suitable for vitamin C determination. 2,6-Dichloroindophenol (DCIP) may be used in the following studies:
  • As redox dye to investigate the efficiency of gold nanoparticles (Au-NP) for enzymatic activity of glucose oxidase (GOx).[1]
  • To compose UVB specific dosimeter.[2]
  • Quantification of vitamin C (L-ascorbic acid) in fruit juices.[3]
  • As substrate in NQO1 assay to investigate the liver cytosolic NQO1 activity spectrophotometrically.[4]
  • Mitochondrial succinate CoQ oxidoreductase (complex II) activity assay.[5]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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이미 열람한 고객

Slide 1 of 1

1 of 1

Hanit Brenner-Lavie et al.
Biochimica et biophysica acta, 1777(2), 173-185 (2007-11-13)
Deleterious effects of dopamine (DA) involving mitochondrial dysfunction have an important role in DA-associated neuronal disorders, including schizophrenia and Parkinson's disease. DA detrimental effects have been attributed to its ability to be auto-oxidized to toxic reactive oxygen species. Since, unlike
Misty Prince et al.
Toxicology letters, 185(3), 180-186 (2009-01-20)
Naturally occurring coumarins possess anti-carcinogenic activities in part by inducing carcinogen-detoxifying enzymes glutathione S-transferase (GST) and/or NAD(P)H quinone oxidoreductase (NQO1). Our goal was to determine whether citrus coumarins induce hepatic GST and/or NQO1 via activation of Nrf2 and the antioxidant
Spectrophotometric evaluation of gold nanoparticles as red-ox mediator for glucose oxidase.
Ramanaviciene A, et al.
Sensors and Actuators B, Chemical, 137(2), 483-489 (2009)
Andrew Mills et al.
The Analyst, 134(5), 845-850 (2009-04-22)
A UVB specific dosimeter is described comprising: a redox dye (2,6-dichloroindophenol, DCIP), a semiconductor (tin(IV) oxide, SnO(2)) and a sacrificial electron donor (glycerol) dispersed in a polymer (hydroxy ethyl cellulose, HEC) film. The dosimeter is blue in the absence of
Further insights toward vitamin c determination and stability proposal of a new quantification method
Vieira CA, et al.
Biosci., 26(2), 296-304 (2010)

질문

1–8 / 8 질문  
  1. Has Sigma Aldrich performed solution stability studies for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 답변
    1. No. Unfortunately, we have not performed solution stability studies on this product.

      도움이 되었습니까?

  2. Has Product D1878, 2,6-Dichloroindophenol sodium salt hydrate, been used as a pH or redox indicator?

    1 답변
    1. Yes. Conn's Biological Stains indicates Dichloroindophenol sodium salt in acid is  red and blue in alkali. The product is colorless when reduced.

      도움이 되었습니까?

  3. Other than use as a reagent for determination of Vitamin C, are there other reported uses of Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 답변
    1. Yes. Conn's Biological Stains indicates Dichloroindophenol sodium salt has been used as an electron receptor, for use in demonstrating NADPH diaphorase and to stain glutathione reductase electrophoresis gels.

      도움이 되었습니까?

  4. Are there published references for Dichloroindophenol sodium salt being used for the determination of Vitamin C?

    1 답변
    1. Yes. Please see: W. Horowitz ed. Official Methods of Analysis of the AOAC Washington D.C. , 777, (1970) and  K. Hiromi et al., Anal. Biochem. 101, 421, (1980).

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  5. Are there substances known to interfere in Vitamin C determination?

    1 답변
    1. Yes. Interfering substances are ferrous, stannous, and cuprous sulfite or thiosulfate ions, and SO2.

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  6. What is the Department of Transportation shipping information for this product?

    1 답변
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  7. What is the solubility for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 답변
    1. During quality control testing, Sigma Aldrich tests solubility at 10 mg/mL in water.  Conn's Biological Stains, 10th Edition states that dichloroindophenol sodium salt is soluble up to 3% in water and up to 2% in ethanol.

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  8. Are the absorbance maxima and the extinction coefficients available for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 답변
    1. Our Analytical Department has run absorbance spectra on many lots of D1878. Using 0.1 M phosphate buffer, pH 8.3 as the solvent, absorbance maxima in the range of 600-605 nm and a mM extinction coefficient of 18.0-19.7 have been reported.

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