475989
MTT
Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan.
동의어(들):
MTT, 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium Bromide, Thiazole Blue
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C18H16BrN5S
CAS Number:
Molecular Weight:
414.32
MDL number:
UNSPSC 코드:
12171500
NACRES:
NA.25
추천 제품
Quality Level
분석
≥98% (silver nitrate titration)
형태
solid
제조업체/상표
Calbiochem®
저장 조건
OK to freeze
불순물
≤0.5% Sulfated ash
색상
yellow
solubility
PBS: 2 mg/mL
양이온 미량물
heavy metals: ≤0.001%
배송 상태
ambient
저장 온도
15-25°C
InChI
1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI key
AZKSAVLVSZKNRD-UHFFFAOYSA-M
일반 설명
Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. Spectrophotometric measurement of MTT-formazan at 540 or 570 nm allows quantitation of cell viability. Used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. An electron acceptor used for studying NADP-dependent dehydrogenases.
생화학적/생리학적 작용
Cell permeable: yes
Primary Target
Used as a direct indicator of cytotoxicity and apoptosis.
Used as a direct indicator of cytotoxicity and apoptosis.
Product does not compete with ATP.
Reversible: no
경고
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
재구성
Following reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 1 month at -20°C.
기타 정보
Liu, Y., et al. 1997. J. Neurochem.69, 581.
Abdallah, M.A. 1980. Eur. J. Biochem. 112, 331.
Abdallah, M.A. 1980. Eur. J. Biochem. 112, 331.
법적 정보
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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