D1542
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride
enzyme inhibitor
동의어(들):
2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride
로그인조직 및 계약 가격 보기
크기 선택
10 MG
₩1,244,695
25 MG
₩2,838,752
₩1,244,695
구입 가능 여부는 고객센터에 문의하십시오.
모든 사진(1)
크기 선택
보기 변경
10 MG
₩1,244,695
25 MG
₩2,838,752
About This Item
실험식(Hill 표기법):
C5H11NO3 · HCl
CAS Number:
Molecular Weight:
169.61
MDL number:
UNSPSC 코드:
12352202
PubChem Substance ID:
NACRES:
NA.77
₩1,244,695
구입 가능 여부는 고객센터에 문의하십시오.
추천 제품
Quality Level
분석
≥98% (TLC)
양식
solid
저장 조건
under inert gas
solubility
water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
저장 온도
2-8°C
SMILES string
Cl.OC[C@H]1NC[C@@H](O)[C@@H]1O
InChI
1S/C5H11NO3.ClH/c7-2-3-5(9)4(8)1-6-3;/h3-9H,1-2H2;1H/t3-,4-,5-;/m1./s1
InChI key
PZGVJCJRMKIVLJ-DEVUXVJFSA-N
유전자 정보
human ... PYGB(5834) , PYGBL(5835) , PYGL(5836) , PYGM(5837)
mouse ... Gaa(14387) , Glb1(12091) , Treh(58866)
rat ... Man2a1(25478) , Pygl(64035) , Si(25588)
일반 설명
1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.[1]
애플리케이션
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.[2]
생화학적/생리학적 작용
Inhibitor of glycogen phosphorylase and α-glucosidases.
주의사항
Extremely hygroscopic, store and handle under argon
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Tetrahedron Letters, 42, 5685-5685 (1986)
A new resorufin-based $\alpha$-glucosidase assay for high-throughput screening
Motabar O, et al.
Analytical Biochemistry, 390(1), 79-84 (2009)
The synthesis from d-xylose of the potent and specific enantiomeric glucosidase inhibitors, 1, 4-dideoxy-1, 4-imino-d-arabinitol and 1, 4-dideoxy-1, 4-imin
Fleet GWJ and Smith PW
Tetrahedron, 42(20), 5685-5692 (1986)
Ze Fan et al.
Neuroscience bulletin, 36(12), 1513-1523 (2020-10-14)
General anesthesia severely affects the metabolites in the brain. Glycogen, principally stored in astrocytes and providing the short-term delivery of substrates to neurons, has been implicated as an affected molecule. However, whether glycogen plays a pivotal role in modulating anesthesia-arousal
Junnan Xu et al.
Frontiers in pharmacology, 9, 873-873 (2018-08-23)
Understanding the mechanistic basis for temozolomide (TMZ)-induced glioma resistance is an important obstacle in developing an effective form of chemotherapy for this type of tumor. Glycogenolysis is known to play an essential role in cellular proliferation and potassium homeostasis and
활성 필터
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