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Merck
모든 사진(1)

주요 문서

C9504

Sigma-Aldrich

Coenzyme Q6

동의어(들):

2,3-Dimethoxy-5-methyl-6-(farnesylfarnesyl)-1,4-benzoquinone, Ubiquinone-30

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About This Item

실험식(Hill 표기법):
C39H58O4
CAS Number:
Molecular Weight:
590.88
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:

생물학적 소스

Saccharomyces cerevisiae

저장 온도

−20°C

SMILES string

COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C)=C(C)C1=O

포장

Sealed ampule.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Mohammad Ozeir et al.
Chemistry & biology, 18(9), 1134-1142 (2011-09-29)
Coenzyme Q (Q), an essential component of eukaryotic cells, is synthesized by several enzymes from the precursor 4-hydroxybenzoic acid. Mutations in six of the Q biosynthesis genes cause diseases that can sometimes be ameliorated by oral Q supplementation. We establish here
Mario H Barros et al.
The Journal of biological chemistry, 280(52), 42627-42635 (2005-10-19)
Deletion of the Saccharomyces cerevisiae gene YOL008W, here referred to as COQ10, elicits a respiratory defect as a result of the inability of the mutant to oxidize NADH and succinate. Both activities are restored by exogenous coenzyme Q2. Respiration is
Beth Marbois et al.
The Journal of biological chemistry, 280(21), 20231-20238 (2005-03-29)
Coenzyme Q (Q) is a redox active lipid essential for aerobic respiration in eukaryotes. In Saccharomyces cerevisiae at least eight mitochondrial polypeptides, designated Coq1-Coq8, are required for Q biosynthesis. Here we present physical evidence for a coenzyme Q-biosynthetic polypeptide complex
Sergio Padilla-López et al.
Biochimica et biophysica acta, 1788(6), 1238-1248 (2009-04-07)
Coenzyme Q is an isoprenylated benzoquinone lipid that functions in respiratory electron transport and as a lipid antioxidant. Dietary supplementation with Q is increasingly used as a therapeutic for treatment of mitochondrial and neurodegenerative diseases, yet little is known regarding
Alejandro Martín-Montalvo et al.
The Biochemical journal, 440(1), 107-114 (2011-08-05)
CoQ(6) (coenzyme Q(6)) biosynthesis in yeast is a well-regulated process that requires the final conversion of the late intermediate DMQ(6) (demethoxy-CoQ(6)) into CoQ(6) in order to support respiratory metabolism in yeast. The gene CAT5/COQ7 encodes the Cat5/Coq7 protein that catalyses

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