810250C

25-NBD Cholesterol

Avanti Research^™ - A Croda Brand 810250C

• 동의어(들): 25-[N-[(7-nitro-2-1,3-benzoxadiazol-4-yl)methyl]amino]-27-norcholesterol
• 실험식(Hill 표기법): C₃₃H₄₈N₄O₄
• CAS Number: 105539-27-3
• Molecular Weight: 564.76
• MDL number: MFCD22416768
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: liquid
• 포장: pkg of 1 × 1 mL (810250C-10mg); pkg of 1 × 1 mL (810250C-1mg); pkg of 1 × 1 mL (810250C-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 810250C
• 농도: 1 mg/mL (810250C-1mg); 10 mg/mL (810250C-10mg); 5 mg/mL (810250C-5mg)
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [N+](=O)([O-])c1c2n[o]nc2c(cc1)N(C(CCC[C@H]([C@H]3[C@@]4([C@H]([C@H]5[C@@H]([C@]6(CC[C@@H](CC6=CC5)O)C)CC4)CC3)C)C)C)C
• InChI: 1S/C33H48N4O4/c1-20(7-6-8-21(2)36(5)28-13-14-29(37(39)40)31-30(28)34-41-35-31)25-11-12-26-24-10-9-22-19-23(38)15-17-32(22,3)27(24)16-18-33(25,26)4/h9,13-14,20-21,23-27,38H,6-8,10-12,15-19H2,1-5H3/t20-,21?,23+,24+,25+,26+,27+,32+,33-/m1/s1
• InChI key: RMGLSQAGXRZCPZ-OVHOIDCTSA-N

설명

일반 설명

25-NBD Cholesterol is a fluorescent derivative of cholesterol. Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group.[1]

애플리케이션

25-NBD Cholesterol can be used as a labeling agent for confocal microscopy in studying endosomal trafficking and vesicle formation.[2]

생화학적/생리학적 작용

Cholesterol is synthesized via a cascade of enzymatic reactions known as the mevalonate pathway. Cholesterol plays a major role in the architecture and stability of the plasma membrane and is also involved in the synthesis of cholecalciferol (Vitamin D3). Cholesterol build up on the walls or arteries causes obstruction of blood flow leading to a serious condition called artherosclerosis.[3][4] It is a precursor for bile acid and for the synthesis of steroid hormones like progesterone, testosterone, cortisol, and aldosterone.[3][5]

포장

5 mL Clear Glass Sealed Ampule (810250C-10mg)

5 mL Clear Glass Sealed Ampule (810250C-1mg)

5 mL Clear Glass Sealed Ampule (810250C-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H319,H331,H336,H351,H361d,H372
• 예방조치 성명서: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• 표적 기관: Liver,Kidney, Respiratory system
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point (°F): does not flash
• Flash Point (°C): does not flash