C7505

L-Cystathionine

≥98% (TLC), suitable for UHPLC

• 동의어(들): (R)-S-(2-Amino-2-carboxyethyl)-L-homocysteine
• 실험식(Hill 표기법): C₇H₁₄N₂O₄S
• CAS Number: 56-88-2
• Molecular Weight: 222.26
• Beilstein: 2505200
• EC Number: 200-295-8
• MDL number: MFCD00036685
• UNSPSC 코드: 12352209
• PubChem Substance ID: 24892965
• NACRES: NA.26

속성

• 제품명: L-Cystathionine, ≥98% (TLC)
• 분석: ≥98% (TLC)
• 양식: powder
• 기술: UHPLC: suitable
• 색상: white
• mp: >300 °C
• 저장 온도: −20°C
• SMILES string: N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O
• InChI: 1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1
• InChI key: ILRYLPWNYFXEMH-WHFBIAKZSA-N

설명

애플리케이션

L-Cystathionine has been used in ultra-performance liquid chromatography for the validation of cystathionine and the correlation of its abundance with vertebrate metamorphosis. It has also been used as an inhibitor of sinusoidal GSH (glutathione) carrier to signify that thiol redox state imbalance is associated with the modulation of autophagy in carcinoma cells.[1]

생화학적/생리학적 작용

L-Cystathionine is an intermediate in the biosynthesis of L-cysteine and methionine.[2][3] It is used as a substrate to differentiate and analyze cystathionine γ-lyase(s).[4] L-Cystathionine is an important non-protein amino acid and is associated with metabolic disorders.[5] In recent studies, L-cystathionine is believed to be the precursor of cyclic imino acid cyclothionine. Cystathioninuria is characterized with imino acid cyclothionine excretion in the urine.[3]

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)