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Merck
모든 사진(4)

문서

C6727

Sigma-Aldrich

L-Cystine dihydrochloride

≥98.0% dry basis, suitable for cell culture, BioReagent, non-animal source

동의어(들):

Cystine dihydrochloride

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C6H12N2O4S2 · 2HCl
CAS Number:
Molecular Weight:
313.22
EC Number:
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

L-Cystine dihydrochloride, from non-animal source, BioReagent, suitable for cell culture, ≥98.0% dry basis

생물학적 소스

non-animal source

제품 라인

BioReagent

분석

≥98.0% dry basis

형태

powder or crystals

광학 활성

[α]20/D -174 to -164 °, c = 2 in 1 M HCl

기술

cell culture | mammalian: suitable

불순물

endotoxin, tested

색상

white to off-white

mp

≥211.36 °C

solubility

2 M HCl: 50 mg/mL

양이온 미량물

As: ≤2 ppm
Fe: ≤30 ppm
NH4+: ≤0.03%
heavy metals: ≤10 ppm

작용기

carboxylic acid
thiol

저장 온도

room temp

SMILES string

Cl.Cl.N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4S2.2ClH/c7-3(5(9)10)1-13-14-2-4(8)6(11)12;;/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12);2*1H/t3-,4-;;/m0../s1

InChI key

HHGZUQPEIHGQST-RGVONZFCSA-N

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관련 카테고리

일반 설명

L-Cystine dihydrochloride is a vital component of biological systems, and its role in protein structure, redox chemistry, and cellular processes makes it a valuable tool in Biology and Chemistry research across a wide range of applications, from understanding fundamental biochemical mechanisms to drug development and nutritional research. L-Cystine is essential for studying protein structure and function. It can be used to create disulfide bonds in proteins, aiding in the formation of protein complexes and the stabilization of protein structures. This is particularly important in biotechnology and pharmaceutical research.

애플리케이션

L-cystine dihydrochloride has been used:

  • as a supplement to study homopropargylglycine update in metabolomics
  • as a supplement in protein synthesis for cell biology and stem cell research
  • to study the effect of lipid peroxidation and ferroptosis by regulation of cysteine and GSH levels in biochemical research

생화학적/생리학적 작용

Cystine is the dimeric form of cysteine. Cysteine is the source of disulfide linkages in proteins and has a role in sulfur transport. It undergoes rapid oxidation to form cystine at physiological pH. L-Cystine is crucial for oxygen production and low density lipoprotein modification by arterial smooth muscle cells. It also has a role in the synthesis of glutathione.

특징 및 장점

  • High-quality compound suitable for multiple research applications
  • Suitable for mammalian cell culture
  • Prepared from non-animal source
  • Tested for Endotoxins

주의사항

hygroscopic

기타 정보

For additional information on our range of Biochemicals, please complete this form.

호환 제품

제품 번호
설명
가격

픽토그램

Corrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Activated human CD4+ T cells express transporters for both cysteine and cystine
Trine Boegh
Scientific Reports (2012)
The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.
The Journal of Biological Chemistry, 262(21) (1987)
The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases
Maisie Lo
Journal of Cellular Physiology, 215 (2008)
Metabolic heterogeneity of tissue-resident macrophages in homeostasis and during helminth infection
Heieis GA et al.
Nature Communications, 4, 5627-5627 (2023)
Robert W. Schrier
Manual of Nephrology (2008)

문서

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

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