C7352

L-Cysteine

from non-animal source, BioReagent, suitable for cell culture, ≥98%

• 동의어(들): (R)-2-Amino-3-mercaptopropionic acid
• Linear Formula: HSCH₂CH(NH₂)CO₂H
• CAS Number: 52-90-4
• Molecular Weight: 121.16
• Beilstein: 1721408
• EC Number: 200-158-2
• MDL number: MFCD00064306
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24892959
• NACRES: NA.75

속성

• 생물학적 소스: non-animal source
• Quality Level: 200
• 제품 라인: BioReagent
• 분석: ≥98%
• 양식: crystalline powder
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin, tested
• 색상: white
• mp: 240 °C (dec.) (lit.)
• solubility: H₂O: 25 mg/mL
• SMILES string: N[C@@H](CS)C(O)=O
• InChI: 1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
• InChI key: XUJNEKJLAYXESH-REOHCLBHSA-N

설명

일반 설명

L-Cysteine is one of the sulfur containing proteinogenic amino acid incorporated into proteins as directed by the genetic code.[1] The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. L-Cysteine is an essential precursor for inorganic sulfates, coenzyme A.[1] Cysteine is an essential and limiting for the formation of glutathione, an important antioxidant, within the cell. Mammalian liver can synthesize L-cysteine and is a semi-essential amino acid. L-cysteine prevents oxidation of nerve cells, aids in maintaining the stability and rigidity of connective tissues. L-cysteine speeds up the healing process of the body and reduces inflammatory reactions. L-cysteine protects testis partially against acrylamide induced toxicity.[1] L-cysteine can prevent DNA damage during cryopreservation and preserves semen quality.[2]

L-Cysteine is a proteinogenic amino acid incorporated into proteins as directed by the genetic code. The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. Cysteine is essential and limiting for the formation of glutathione, an important antioxidant, within the cell.

애플리케이션

L-Cysteine has been used:

• as a media supplement in Trypticase-Yeast Extract-Iron-Serum (TYI-S-33) media for the culture of Giardia lamblia,[3] to make enzyme solution in Dulbecco′s modified Eagles medium (DMEM) to establish hippocampus culture[4]
• to test its protective effect on acrylamide induced toxicity in testis[1]
• in the preparation of tris acetic acid extender solution for cryopreservation of semen[2]
• as an additive to make papain digestion solution[5]

생화학적/생리학적 작용

NMDA glutamatergic receptor agonist.

기타 정보

L-Cysteine is used to supplement cell culture media. This product is a non-animal source amino acid useful for serum-free media formulations intended for biomanufacturing applications.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves